Hypertrophy
Conditions
Keywords
Omega-3, Krill oil, Protein, Exercise
Brief summary
The aim of the current study is to find out if krill oil can increase muscle building processes in response to resistance (weightlifting) type exercise. Others aim are to determine the effects of krill protein, and the interaction of krill oil and protein, on muscle building processes in response to resistance (weightlifting) type exercise.
Interventions
DIETARY_SUPPLEMENTKrill oil
Krill oil will be supplemented to see if they can gain strength and/or muscle mass following supplementation.
DIETARY_SUPPLEMENTKrill protein
Krill protein will be given to the participant following a resistance exercise bout.
DIETARY_SUPPLEMENTVegetable oil
This will be the control against the Krill oil
DIETARY_SUPPLEMENTCarbohydrate
This will be the control for the Krill protein
Sponsors
Aker BioMarine
University of Glasgow
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
All supplements with be colour and flavour matched
Intervention model description
Parallel 2x2 factorial design
Eligibility
Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Be 60 years old or older * Have a BMI of less than 35kg/m2 * Be participating in structured exercise for less than 2h per week
Exclusion criteria
* Diabetes * Severe cardiovascular disease * Seizure disorders, * Uncontrolled hypertension (\>150/90mmHg at baseline measurement) * Cancer or cancer that has been in remission \<5 years * Ambulatory impairments which would limit ability to perform assessments of muscle function * Dementia * Taking medication known to affect muscle (e.g., steroids) * Have an implanted electronic device (e.g., pacemaker/defibrillator/insulin pump), * Anticoagulant therapy * Allergies to seafood * Regular consumption of more than 1 portion of oily fish per week.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-exercise muscle protein synthesis | 3-7 hours | Muscle protein synthesis measured 3-7h after a single bout of resistance exercise |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Muscle thickness | Change from baseline to 8 weeks | Vastus lateralis muscle thickness measured by ultrasound |
| Change in grip strength | Change from baseline to 8 weeks | Grip strength measured with a Jamar dynamometer |
| Change in fat mass | Change from baseline to 8 weeks | Whole body fat mass measured by BIA |
| Change in muscle strength | Change from baseline to 8 weeks | Knee extensor muscle strength measured isometrically |
| Change in lean mass | Change from baseline to 8 weeks | Whole body lean mass measured by BIA |
| Change in balance | Change from baseline to 8 weeks | Ability to stand for 10 seconds in full tandem, semi-tandem and feet together |
| Change in gait speed | Change from baseline to 8 weeks | Time taken to walk 4 metres at a normal walking pace |
| Basal muscle protein synthesis | 0-3 hours | Muscle protein synthesis measured from 0-3h after an overnight fast |
| Change in Erythrocyte fatty acid profile | Change from baseline to 8 weeks | Erythrocyte fatty acid profile |
| Change in Chair rise time | Change from baseline to 8 weeks | Time taken to get up and down from a chair 5 times |
Countries
United Kingdom
Outcome results
None listed