Postoperative Pain
Conditions
Keywords
DEXMEDETOMİDİNE, REMİFENTANYL, pituitary SURGERY
Brief summary
In patients with pituitary adenoma scheduled for endoscopic transsphenoidal pituitary surgery, it was aimed to compare the efficacy of postoperative pain relief of a selective α-2 agonist Dexmedetomidine and the rapid and short-acting opioid Remifentanil using the Numerical Rating Scale (NRS) administered alongside propofol in perioperative maintenance anesthesia. .
Interventions
DRUGDexmedetomidine
Efficacy of dexmedetomidine on postoperative pain in patients undergoing transsphenoidal pituitary surgery
DRUGRemifentanyl
Efficacy of remifentanyl on postoperative pain in patients undergoing transsphenoidal pituitary surgery
Sponsors
Kocaeli University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* 18-65 years old * ASA-1 and ASA-2 patients
Exclusion criteria
* Patients in need of postoperative intensive care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative pain scale | at post anesthesia care unit (T1) | Comparison of postoperative Numerical Rating Scale(NRS) values of both study arms(min 0, max 10; 10 is unbearable pain ) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| need for analgesics | Additional analgesic drug requirements at post anesthesia care unit (T1) | Comparison of whether there is a need for additional POSTOPERATIVE analgesic medication |
| Comparison of postoperative nausea-vomiting rate | at post anesthesia care unit (T1) | Comparison of postoperative nausea-vomiting rate |
Countries
Turkey (Türkiye)
Outcome results
None listed