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Craniofacial Morphology And Sella Turcica Bridging Associated With Third Molar Agenesis.

Third Molar Agenesis Related To Craniofacial Pattern And Sella Turcica Bridging: A Retrospective Cephalometric Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05771246
Enrollment
400
Registered
2023-03-16
Start date
2023-03-06
Completion date
2023-06-07
Last updated
2024-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Agenesis

Brief summary

The aim of this retrospective study is to analyze the third molar agenesis with respect to sella turcica bridging and other craniofacial patterns in patients asking for orthodontic consultation. The main question\[s\] it aims to answer are: * is there a relationship between third molar agenesis and sella turchina bridging? * is there a relationship between third molar agenesis and craniofacial patterns?

Detailed description

Patients referring for orthodontic consultation at the Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy, will be enrolled for the study according to the inclusion criteria. For each patient, lateral cephalometric radiograph and panoramic radiograph will be performed. For each lateral cephalometric radiograph, a cephalometric tracing will be performed with DeltaDent software (version 2.5.12, Outside Format, Pandino, Italy). Riedel's ANB angle \[Riedel 1952\] has been chosen to determine patients' skeletal class. Steiner's SN\^GoGn angle \[Steiner 1953\] has been chosen to evaluate skeletal divergence. Facial axis (BaNa\^CCGn), Lower Facial Height (LFH) and mandibular plan angle (FH\^GoMe) from Rickett's analysis \[Rickett's 1961\] have been adopted to determine facial growth. According to Jaraback's cephalometric analysis \[Jaraback 1985\], saddle angle, articular angle, upper gonial angle, lower gonial angle will be measured to assess the growth pattern. Linear measurements of sella depth, sella diameter and interclinoid distance \[Silverman 1957; Kisling 1966\] will be calculated. Linear regressions between craniofacial patterns, sella turcica bridging and third molar agenesis will be calculated. A control group with no third molar agenesis will be provided.

Interventions

Panoramic and lateral cephalometric radiographs with cephalometric analysis will be performed.

Sponsors

University of Pavia
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
8 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* G stage of Demirjian's classification for third molar maturation or absence of third molar germs * Patients with one lateral cephalometric digital radiograph executed in Natural Head Position (patients were asked to keep the teeth in contact and the lips relaxed). * Patients with panoramic radiograph;

Exclusion criteria

* Ascertained previous surgical extraction/s of third molar/s * Orthopedic/orthodontic therapy * Orthognathic surgery.

Design outcomes

Primary

MeasureTime frameDescription
Linear regression between third molar agenesis and ANBBaselineANB is calculated according to Riedel's analysis: angle formed between Point A (maxillary sovraspinal point), point B (Bubmental mandibular point) and N (Nasion)
Linear regression between third molar agenesis and Interclinoid DistanceBaselineDistance between tuberculum sella (TS) and dorsum sella (DS).
Linear regression between third molar agenesis and Sella Depth.BaselineDistance of a line dropped perpendicular from the interclinoid distance to the deepest point of the sella floor.
Linear regression between third molar agenesis and Sella DiameterBaselineDistance between tuberculum sella and the farthest point on the inner wall of the sella.
Linear regression between third molar agenesis and Sn^GoGn.BaselineSteiner's Sn\^GoGn is the angle formed between 2 planes: cranial base line (SN) and mandibular plane (GoGn)
Linear regression between third molar agenesis and ArGo^GoGnBaselineJaraback's Ar\^Go\^Gn is the angle formed between the 2 planes: ArGo and GoGn

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026