Post Operative Pain
Conditions
Brief summary
All patients admitted in National Cancer institute, Cairo University for breast surgeries will be investigated for inclusion criteria in the current study. And will be enrolled if fulfilled the criteria into 2 groups .70 patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 35) , and the paravertebral group (group P, n =35) * All patients will do Ultrasound-guided ESPB for group E and PVB for group P before receiving general anesthesia * Postoperatively Patients in both groups will receive intravenous morphine 3 mg as rescue analgesic
Detailed description
* 70patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 35) , and the paravertebral group (group P, n =35) * All patients will do Ultrasound-guided ESPB for group E and PVB for group P before receiving GA * Postoperatively Patients in both groups will receive intravenous morphine 3 mg as rescue analgesic. * Random numbers were generated using a computer-generated randomization code and were sealed in an opaque envelope. Randomization was conducted by a person who was not involved in the study. * An independent observer who was blind to the group assignment checked the intraoperative and postoperative data. * VAS pain score immediately postoperative and at 2,4,6, 8,12,18,24,36 ,48hrs.postoperative.
Interventions
PROCEDUREERECTOR SPINAE PLANE BLOCK and PARAVERTEBRAL BLOCK:
catheter will be placed for ERECTOR SPINAE PLANE BLOCK
PROCEDUREPARAVERTEBRAL BLOCK:
catheter will be placed for PARAVERTEBRAL BLOCK
Sponsors
National Cancer Institute, Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Masking description
An independent observer who will be blind to the group assignment checked the intraoperative and postoperative data also patient will be be blinded also
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
.Physical status ASA II. . Patients (age 20-70yrs) scheduled for breast surgeries for breast cancer under general anesthesia
Exclusion criteria
.History of psychological disorders. * Known sensitivity or contraindication to local anesthetics. * Localized infection at the site of block. * patients with coagulopathy or an (INR ≥ 2)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total 48 hours Post-operative opioid consumption to keep VAS score ≤4. | 48 hours postoperative | the VAS score rating, in which 0 = no pain and 10 = worst possible pain. both during rest and movement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 1st request of analgesia | 48 hours postoperative | 1st request of analgesia , any hemodynamic instability and complications |
Countries
Egypt
Contacts
Primary Contactsuzan adlan, lecturer
Backup ContactTaher saed, lecturer
Outcome results
None listed