Active Navigation Training

Active Navigation Training: an Innovative Embodied-based Training System for Spatial Navigation in Aging

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05768620

Acronym

ANTaging

Enrollment

Registered

2023-03-14

Start date

2020-04-01

Completion date

2023-07-01

Last updated

2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment, Spatial Navigation

Keywords

virtual reality

Brief summary

Pilot testing and development of an immersive virtual reality system for spatial navigation training in mild cognitive impairment syndrome.

Interventions

OTHERCAVE

The training is designed to train spatial navigation and memory and in particular egocentric and allocentric processes

OTHERTAU

This is the usual care used to train visuospatial processes

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Intervention model description

Proof-of-concept trial

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

* clinical diagnosis of mild cognitive impairment * absence of severe cognitive deterioration as assessed by the Italian version of the MMSE (Magni et al. 1996) * age ≥ 60

Exclusion criteria

* the presence of acute stroke/transient ischemic attack; * the presence of other concomitants severe neurological/psychiatric diseases; * history of traumatic brain injury with loss of consciousness; * physical/functional deficits that could affect the use of immersive virtual reality; * severe visual deficiency; * the presence of recurrent vertigo.

Design outcomes

Primary

Measure	Time frame	Description
Change in Corsi supra-span test	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up	Scores range from 0 to 29.16, higher scores indicate better visuospatial learning
Change in Manikin Test	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up	Scores range from 0 to 1, higher scores indicate better visuospatial mental rotation

Secondary

Measure	Time frame
Mini-mental state examination	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up
Trail-making test part A and B	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up
Corsi Block Tapping	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up
Digit span forward	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up
Raccontino (6 Dicembre) (immediate-delayed-forgetting)	After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026