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Assignment of the Verbal Component Score and Addition of Pupil Reaction to the Glasgow Coma Scale

Investigation of the Effect of Assigning Verbal Component Score to Glasgow Coma Scale in Patients With Traumatic Brain Injury and Adding Pupil Reaction to Determining Mortality/Morbidity in Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05767502
Enrollment
199
Registered
2023-03-14
Start date
2023-02-20
Completion date
2024-06-01
Last updated
2023-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Injuries, Traumatic

Keywords

GCS, GCS-Pupil score, Brain trauma, Consciousness

Brief summary

In this study, it is aimed to determine the prognostic value of GCS-P and the GCS-P score, which is formed by assigning a verbal score, in patients with traumatic brain injury, where all parameters can be evaluated. In the model to be created, a new total score will be obtained with Motor score + Eye Response + assigned verbal Score-Pupil score and this score will be compared with GCS and GCS-Pupil score.

Interventions

DIAGNOSTIC_TESTGCS-Pupil score

GCS+attributed verbal score- Step 1 to obtain pupillary score: * Patients with a motor (M) and eye-opening response (E) total score between 2 and 6 are assigned a verbal score of +1 * Patients with an M+E score of 7 are assigned a verbal score of +2 * Patients with an M+E score of 8-9 are assigned a verbal score of +4 * Patients with an M+E score of 10 are assigned a verbal score of +5 GCS+attributed verbal score- Step 2 to obtain the pupillary score: The total score is obtained by subtracting the pupil score from the score obtained in the 1st step. Pupil score is scored as follows; * 0 points if both pupils react to light, * 1 point if a pupil does not react to light and has anisocoria, * 2 points if both pupils do not react to light

Sponsors

Uludag University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Admitted to hospital due to traumatic brain injury, * 18 years and older, * who were alive at the time of admission, * Patients whose GCS and pupil reactivity can be evaluated completely.

Exclusion criteria

* Younger than 18, * Not alive at the time of admission, * Patients whose GCS score and pupil reactivity are not correctly evaluated (facial trauma, past eye diseases or eye defects, etc.).

Design outcomes

Primary

MeasureTime frameDescription
MORTALITYFrom admission to discharge, an average of 1 weeksDeath of the patient while in the hospital
MORBIDTIYFrom admission to discharge, an average of 1 weeksPatients with a Glasgow Outcome score of 2 and 3 (Each patient can get 1-5 points from the Glasgow Outcome score. A low score indicates a negative result.

Secondary

MeasureTime frameDescription
MORTALITY3 months after hospital dischargeDeath within 3 months after hospital discharge
MORBIDITY3 months after hospital dischargeA Glaskow Coma Outcome Score of 2 and 3 at the end of 3 months after discharge from the hospital. (Each patient can get 1-5 points from the Glasgow Outcome score. A low score indicates a negative result)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026