RSV Infection
Conditions
Brief summary
The study will be a multicenter, hospital-based retrospective study. We plan to collect the clinical and laboratory data among all hospitalized ARTI cases in three hospitals in Wuhan from June 1, 2020 to May 31, 2023 and then analyze the epidemiological and clinical characteristics of RSV infection, clarify the gene types of epidemics under 5 years old children after the outbreak in Wuhan, China.
Interventions
OTHERObservation
clinical manifestation (body temperature, fever days before admission, cough, red throat/sore throat, runny nose, shortness of breath, wheezing, vomiting), physical signs (auscultation of lungs, X-ray results), length of stay, therapeutic measures (oxygen therapy, ICU admission, antibiotic therapy, etc.)
Sponsors
Tongji Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to 5 Years
Healthy volunteers
No
Inclusion criteria
①Admission age \<5 years old ②Clinical diagnosis of acute respiratory tract infections
Exclusion criteria
Hospital acquired ARTI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of patients with fever | at admission | number of patients with fever |
| number of patients with cough | at admission | number of patients with cough |
| number of patients with shortness of breath | at admission | number of patients with shortness of breath |
| number of patients with shortness of wheeze | at admission | number of patients with shortness of wheeze |
| number of patients with shortness of vomit | at admission | number of patients with shortness of vomit |
| number of patients with shortness of rale | at admission | number of patients with shortness of rale |
| number of patients with shortness of stridor | at admission | number of patients with shortness of stridor |
| age | at admission | age |
| gender | at admission | female/male |
| number of patients with underlying disease | at admission | underlying disease include immune deficiency, CHD, BPD, BO, bronchiectasis and asthma and so on |
| Imaging examination results | through study completion, an average of 1 year | X-Ray/CT |
| length of hospital stay length of stay length of stay | through study completion, an average of 1 year | length of hospital stay |
| number of patients with treatment of antibiotic | through study completion, an average of 1 year | number of patients with treatment of antibiotic |
| number of patients with treatment of immunoglobulin | through study completion, an average of 1 year | number of patients with treatment of immunoglobulin |
| number of patients with treatment of glucocorticoids | through study completion, an average of 1 year | number of patients with treatment of glucocorticoids |
| number of patients with treatment of oxygen inhalation | through study completion, an average of 1 year | number of patients with treatment of oxygen inhalation |
| number of patients with treatment of ventilation | through study completion, an average of 1 year | number of patients with treatment of ventilation |
| direct medical cost | through study completion, an average of 1 year | direct medical cost |
| proportion of different virus genotype | through study completion, an average of 1 year | virus genotype include A, B and C |
| F protein gene sequence | through study completion, an average of 1 year | F protein gene sequence |
| number of patients infected with bacteria | through study completion, an average of 1 year | number of patients infected with bacteria |
| number of patients infected with virus | through study completion, an average of 1 year | number of patients infected with virus |
| number of patients infected with fungus | through study completion, an average of 1 year | number of patients infected with fungus |
Countries
China
Outcome results
None listed