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Effect of Advanced Care at Home vs. Traditional Brick-and-Mortar Hospital Care in Acutely Ill Adults: A Pragmatic Clinical Trial

Effect of Advanced Care at Home vs. Traditional Brick-and-Mortar Hospital Care in Acutely Ill Adults: A Pragmatic Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05766956
Enrollment
1150
Registered
2023-03-13
Start date
2023-07-10
Completion date
2024-12-30
Last updated
2025-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Illness

Brief summary

The purpose of this study is to compare two care delivery models that are currently being implemented in routine practice settings. The findings from this study will inform future clinical decision making, such as which patients might be more suited for which care delivery model.

Interventions

Inpatient hospitalization offered in the home setting.

Inpatient hospitalization offered in the hospital setting.

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients, 18 years of age and older * Present to one of the participating hospitals * Have a chief complaint of one of the target diagnoses * Are within a certain geographical area (based on zip codes) * Have a health insurance plan that covers ACH services * Have the capacity to consent or could assent with the consent of a health care proxy who is physically present

Exclusion criteria

* Not suitable for ACH or inpatient hospital care as determined by the patient's clinical team * Do not have the capacity to consent or assent with the assistance of a health care proxy

Design outcomes

Primary

MeasureTime frameDescription
The primary outcome is a composite outcome of all-cause mortality30 days post-dischargeThe rate of death
30-day readmission30 days post-dischargeReadmission between discharge from ACH/traditional inpatient hospital care and 30 days post-discharge

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026