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Evaluation of Lung Metastases Based on Ultrashort Echo Time MRI

The Diagnostic Value of Lung Ultrashort Echo Time MRI for Potential Lung Metastases in Children With Hepatoblastoma

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05763173
Enrollment
65
Registered
2023-03-10
Start date
2023-01-01
Completion date
2024-02-29
Last updated
2024-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatoblastoma, Radiology

Brief summary

Analyze the diagnostic efficiency (including performance, diameter, and location of nodules) of UTE-MRI in lung metastases of hepatoblastoma with chest CT as gold standard

Interventions

None listed

Sponsors

RenJi Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 14 Years

Inclusion criteria

* Children diagnosed as hepatoblastoma (including treated with neoadjuvant chemotherapy but not surgery) * Recent chest CT scan (within 14 days) * No MRI contraindications * The guardian of the children are willing to undergo the examination after full communication and informed consent

Exclusion criteria

* MRI contraindications (including but not limited to: contrast medium allergy; Claustrophobia;Metal implants;chronic kidney disease≥stage 3 (glomerular filtration rate \< 60 mL min-1 (1.73 m2)-1)) * Patients with hepatoblastoma aged 14 years and above * Children after surgery for hepatoblastoma * Application of any contrast medium within 24 h before the MRI and/or CT examinations * There is a concomitant medical condition (e.g. poorly controlled hypertension, severe diabetes, neurological or psychiatric illness, etc.) or any other condition that would seriously endangers the subject's safety, may confuse the study results, or may interfere with the subject's completion of the study according to the investigator's judgment.

Design outcomes

Primary

MeasureTime frameDescription
UTE-MRI assessment of lung metastases with chest CT as gold standardBaseline to 14 daysAnalyze the diagnostic efficiency (including performance, diameter, and location of nodules) of UTE-MRI in lung metastases of hepatoblastoma.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026