Ligament; Laxity, Recurrent Patellar Dislocation
Conditions
Brief summary
The purpose of this study is to assess correlation between recurrent patella dislocation and genetic polymorphism rs1800012 of the COL1A1 Gene and rs12722 of the COL5A1 Gene.
Detailed description
After being informed about the study and potential risk all of participants were performed phisical examination and genetic test. In the study we established two groups: In first group- 50 patients with recurrent patellar dislocation and without any genetic disorders. In the second one 200 patients without recurrent patellar dislocation and genetic disorders. All pediatric patients were between 7 and 17 years old in two groups respectivly.
Interventions
DIAGNOSTIC_TESTgenetic test
COL1A1 or COL5A1 genetic test
OTHERBeighton joint laxity test
Based on Beighton scale.
Sponsors
Polish Mother Memorial Hospital Research Institute
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
7 Years to 17 Years
Healthy volunteers
Yes
Inclusion criteria
• First-time diagnosed or recurrent patellar dislocation patient from 7 to 17 age years old.
Exclusion criteria
* Patient's age under 7. * Presence of genetic diseases such as: Down's syndrome or Marfan's syndrome. * Metabolic disorders. * Previous knee surgeries. * Cartilage and bone fractures in the knee. * No consent for examination from the legal guardian.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patients with recurrent patellar dislocation | 2022-2023 | Patients with recurrent patellar dislocation |
| Control group without obvious joint hipermobility | 2022-2023 | Control group without obvious joint hipermobility |
Countries
Poland
Outcome results
None listed