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Analgesic Territory Assessment of the Spinal Erector Block Using Pupillometry

Analgesic Territory Assessment of the Spinal Erector Block Using Pupillometry

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05762159
Acronym
TEASER
Enrollment
30
Registered
2023-03-09
Start date
2023-03-10
Completion date
2024-05-07
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Local

Keywords

spinal erector block, pupillometry, loco-regional anesthesia, osteosynthesis

Brief summary

Few works have studied the area of analgesia covered by the spinal erector block in an objective manner, especially on the cephalo-caudal spread. The available data are dissection works or subjective data such as thermoalgesic or epicritic sensitivity. This information would however be relevant in order to propose a better analgesia. Indeed, it could explain certain failures by insufficient diffusion of the block. The use of a multistage block could be relevant, especially in the case of osteosynthesis on several vertebral levels.

Detailed description

Pupillometry makes possible to monitor analgesia based on the pupillary dilation reflex to pain. The goal is to establish an objective mapping of these type of analgesia from these data.

Interventions

data collected: * Morphological data of the patients * Data of the erector block realization * Pupillometric data :the variation of the pupil size on stimulation (in percentage of the base diameter)

Sponsors

Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients receiving erector spinae block for pain management of spinal osteosynthesis

Exclusion criteria

* Patient refusal * Known allergy to local anesthetics * Contraindication to locoregional anesthesia (haemostasis disorder, infection, peripheral neuropathy) * Technical impossibility to perform a spinal erector block * Pathology with dysautonomia altering the pupillary reflex: diabetes mellitus with diabetic retinopathy, multiple sclerosis, systemic amyloidosis, uncontrolled hypertension, glaucoma * Current treatment likely to alter pupillary dilation reflex to pain : antiemetic (droperidol, metoclopramide), alpha-2 agonist (clonidine) * Serious psychiatric history * Drug abuse * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
variation of the pupil size (in percentage)During the surgeryEvaluation the territory covered by the spinal erector block by variation of the pupil size (in percentage). Variation of the pupil size on stimulation will allow to deduce if the dermatome is covered by the spinal erector block analgesia.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026