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A Cohort Study of Patients With Intracranial Hemorrhage

China Cohort of Patients With Intracranial Hemorrhage

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05760950
Enrollment
300
Registered
2023-03-09
Start date
2020-12-11
Completion date
2023-06-01
Last updated
2023-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracerebral Hemorrhage

Brief summary

As one of the most serious forms of acute stroke, the early mortality rate of intracerebral hemorrhage(ICH) can be as high as 30-40%. The incidence of intracerebral hemorrhage increases with the increase of age. Under the circumstance of the aggravation of aging in China, intracerebral hemorrhage brings a certain burden to families and society. The results of several studies in recent years have failed to provide new therapeutic approaches for the treatment of cerebral hemorrhage. Therefore, novel therapeutic approaches is urgently needed for ICH. Primary and secondary prevention, acute inpatient care, and poststroke rehabilitation are all critical. The objective of this cohort study is to explore factors that might influence the long-term prognosis of patients with ICH and to further identify new potential targets for intervention.

Detailed description

The observational cohort study will be used to find the possible treatment methods and predictors of functional outcome. The medical records of patients will be collected, including age, sex, comorbid conditions, toxic habits, use of medications (antiplatelets, anticoagulants, and antihypertensives), systolic and diastolic blood pressure, Glasgow Coma Scale (GCS) score, and National Institutes of Health Stroke Scale (NIHSS) score on admission. Image data will also be collected. Follow-up information will be obtained from the medical records or telephone interviews.

Interventions

Routine clinical treatment is based on the latest international guidelines for intracerebral hemorrhage.

Sponsors

Capital Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Primary intracerebral hemorrhage * Over 18 year-old

Exclusion criteria

* Secondary intracerebral hemorrhage, such as aneurysmal, hemorrhagic transformation of ischemic stroke, cavernomas, arterio-venous malformations, central venous thrombosis, trauma-related, or tumor. * Pregnant patients. * Any condition which, in the judgment of the investigator, might increase the risk to the patient.

Design outcomes

Primary

MeasureTime frameDescription
Functional outcome90-dayevaluated by modified Rankin Scale

Secondary

MeasureTime frameDescription
Neurological deterioration14-dayevaluated by NIHSS or GCS
Functional outcome1-yearevaluated by modified Rankin Scale
Cerebrovascular disease event2-yearischemic and hemorrhagic events

Countries

China

Contacts

Primary ContactXunming Ji
jixm@ccmu.edu.cn010-83199430
Backup ContactMengke Zhang
zwzmk985@126.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026