Healthy
Conditions
Keywords
recovery, muscle endurance, exercise capacity, microalgae, inflammation
Brief summary
The purpose of this investigation is to examine the effects of consuming a new dietary microalgae based supplement vs. placebo on neuromuscular function, energy utilization, soreness, perceptual wellness, swelling, and markers of muscle damage and inflammation in healthy young men before and after an acute exercise-induced muscle damage protocol (downhill running), and influence on endurance capacity after prolonged consumption.
Interventions
DIETARY_SUPPLEMENTMicAlgae
2 months of supplementation with an innovative microalgae based ingredient
DIETARY_SUPPLEMENTPlacebo
2 months of supplementation with a placebo (Maltodextrin)
Sponsors
University of Central Florida
Microphyt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Male participants * Healthy as assessed by Medical and activity history questionnaire (MHQ) * Recreationally active according to American College of Sports Medicine guidelines * Able to provide written and dated informed consent to participate in the study
Exclusion criteria
* Untrained * Any response of yes on the PAR-Q+ * Physical limitations preventing running, countermovement jump, and strength (peak isometric torque and peak isokinetic torque) assessments
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Neuromuscular function | From 0 to week 4 | isokinetic peak torque in Newton per meter (N/m) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Soreness and perceptual wellness | From 0 to week 4 | Evaluated using using a 100-point numerical pain rating scale anchored with 0= no pain to 100= the most intense pain sensation imaginable after exercise-induced muscle damage protocol |
| Energy utilization (Oxygen consumption - VO2) | From 0 to week 4 | Running economy during a 5-minute run at 80% of the speed at VO2max with gaz exchange analyzis |
| Isokinetic neuromuscular function | From 0 to week 8 | peak torque in Newton per meter (N/m) |
| Isometric neuromuscular function | From 0 to week 8 | peak torque in Newton per meter (N/m) |
| Swelling - Muscle thickness (mm or cm) | From 0 to week 4 | Evaluated using musculoskeletal ultrasound |
| Swelling - overall thigh circumference (mm or cm) | From 0 to week 4 | Evaluated using musculoskeletal ultrasound |
| Endurance capacity | From 0 to week 4 | Maximal oxygen consumption (VO2max) determined during graded exercise test |
| lactate dehydrogenase (U/L) | After 4 weeks of supplementation | Blood marker analyzis |
| Myoglobin (ug/l) | After 4 weeks of supplementation | Blood marker analyzis |
| Interleukin-6 (pg/ml) | After 4 weeks of supplementation | Blood marker analyzis - inflammation |
| Tumor necrosis factor-α (ug/ml) | After 4 weeks of supplementation | Blood marker analyzis - inflammation |
| C-reactive protein (mg/l) | After 4 weeks of supplementation | Blood marker analyzis - inflammation |
| Isometric Neuromuscular function | From 0 to week 4 | Peak torque in Newton per meter (N/m) |
| Creatine kinase (UI/I) | After 4 weeks of supplementation | Blood marker analyzis |
Countries
United States
Outcome results
None listed