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Safety of Endoscopic Thyroidectomy Via Retro-Auricular Single-Site Approach, Transoral Approach and Transareola

Single-center, Retrospective Study of Retro-Auricular Single-Site Endoscopic, Transoral Endoscopic Thyroidectomy Vestibular Approach and Transareola Endoscopic Thyroidectomy in Patients With Early Stage Papillary Thyroid Carcinoma

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05760690
Enrollment
160
Registered
2023-03-08
Start date
2015-01-01
Completion date
2024-12-01
Last updated
2024-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Papillary Thyroid Carcinoma

Keywords

Papillary Thyroid Carcinoma Laparoscopy, Endoscopic Thyroidectomy, Retroauricular Single-site approach, Transoral Endoscopic Thyroidectomy Vestibular Approach, Transareola Endoscopic Thyroidectomy

Brief summary

The goal of this retrospective study is to compare the safety and efficiacy of endoscopic thyroidectomy via retro-auricular single-site approach, transoral endoscopic thyroidectomy vestibular approach and transareola approach.

Interventions

The strap muscles and the sternocleidomastoid muscle were separated. Upper parathyroid and lower parathyroid glands were identified and preserved. The recurrent laryngeal nerve (RLN) was identified,A lobe of thyroid specimen and central lymph nodes were dissected.

The patient was placed in a supine position with slight neck extension under nasotracheal intubation. The mouth was garbled with povidone iodine before surgery. Three laparoscopic ports (a 10- to 15-mm port at midline and two 5-mm ports at the lateral junction between the canine and first premolar teeth)were inserted under the lower lip at the oral vestibular area.The strap muscleswere separated in the midline to expose the thyroid and trachea. The recurrent laryngeal nerve (RLN) was identified at the insertion to the larynx, then followed downandparallel tothe trachea inferiorly.

PROCEDURETransareola Endoscopic Thyroidectomy

The patient was in supine position. Incision was made inside the right areola and a 10mm puncture device was placed, subcutaneous separation rod was used to separate the space, and a 30° endoscope was introduced, puncture device was placed in a 5mm incision on the left areola, ultrasonic knife free flap was used, subcutaneous separation space was placed in the upper sternal segment, and a 5mm puncture device was placed outside the right areola. The anterior cervical flap was further dissociated to establish a space. The median cervical line was cut to cut off the isthmus of the thyroid, and the tracheal fascia ligament of the thyroid was separated and the nerve was exposed to protect the nerves. Then remove the lobe of thyroid and central lymph nodes

Sponsors

Sun Yat-sen University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Age 18-70 years old, no gender restrictions. 2. Fine-needle aspiration cytology(FNA) confirmed papillary thyroid carcinoma(PTC). 3. Early stage PTC (stage T1N0M0). 4. Preoperative ultrasonography showed unilateral glandular lobe malignant tumor and the largest diameter was not more than 2cm, without cervical lymph node metastasis and extensive metastasis. 5. Patients undergoing thyroid lobectomy and central lymph node dissection. 6. Patients who have signed an approved Informed Consent.

Exclusion criteria

1. Patients who do not accept case data collection for various reasons. 2. The clinical data unfit this study (at the discretion of the investigator). 3. Patients who have undergone neck surgery or radiotherapy before this trail. 4. Patients who have uncontrolled hyperthyroidism.

Design outcomes

Primary

MeasureTime frameDescription
C-reactive protein,CRP1 weekthe level of CRP before and after operation

Secondary

MeasureTime frameDescription
Serum Amyloid A,SAA1 weekthe level of CRP before and after operation
blood loss1 weekThe volume of blood loss during operation
VAS pain score2 days after operationPostoperative VAS score was recorded
number of lymph nodes1 week after operationPostoperative specimen Postoperative specimen Postoperative specimen Postoperative specimen the number of lymph nodes in postoperative specimens

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026