HIV Infections
Conditions
Brief summary
The project aims to assess the level of oxidative stress biomarkers in HIV patients on effective antiretroviral treatment in correlation with other therapeutic, clinical, and viro- immunological parameters. The analysis aims to better characterize the patient on treatment through an innovative approach based on two specific tests for complementary assessment of total oxidant and anti-oxidant plasma capacity.
Interventions
OTHERblood sampling
Blood sampling for evaluation of oxidative stress markers
Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ART-treated PLWH * HIV-1 RNA\< 50 copies/mL * Stable ART therapy (at least 48 weeks) * Signature of informed consent for study participation
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of the levels of total oxidant and antioxidant plasma capacity | 1 year | Quantify the levels of total oxidant and antioxidant plasma capacity antioxidant |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between level of oxidative stress biomarkers and several factors | 1 year | Evaluation of the impact of therapeutic, viro-immunologic, clinical, and demographic factors on the level of oxidative stress biomarkers. |
Countries
Italy
Outcome results
None listed