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The IGNITE for Kids Study on Concentrated Investment in Black Neighborhoods and Child Health and Well-Being

A Randomized Controlled Trial of Concentrated Investment in Black Neighborhoods to Address Structural Racism as a Fundamental Cause of Poor Child Health

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05760001
Enrollment
221
Registered
2023-03-08
Start date
2023-06-10
Completion date
2026-02-13
Last updated
2026-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Economic Problems, Environmental Exposure, Financial Stress, Health Behavior, Health, Subjective, Mental Health Wellness

Brief summary

Black children and adults in the United States fare worse across nearly every health indicator compared to White individuals. In Philadelphia, the location of this study, these health disparities result in a stark longevity gap, with average life expectancies in poor, predominantly Black neighborhoods being 20 years lower than in nearby affluent, predominantly White neighborhoods. The investigators will conduct a cluster randomized controlled trial (RCT) of a suite of place- based and financial-wellbeing interventions at the community, organization, and individual/household levels that address the social determinants of racial health disparities. At the community level, the investigators address underinvestment in Black neighborhoods by implementing vacant lot greening, abandoned house remediation, tree planting, and trash cleanup. At the organization level, the investigators partner with community-based financial empowerment providers to develop cross-organizational infrastructure to increase reach and maximize efficiency. At the individual/household levels, the investigators increase access to public benefits, financial counseling and tax preparation services, and emergency cash assistance. The investigators will test this "big push" intervention in 60 Black neighborhood micro-clusters, with a total of 480 children. The investigators hypothesize that this "big push" intervention will have significant impact on children's health and wellbeing.

Detailed description

Black individuals in the United States fare worse than White individuals across almost every social, economic, and health indicator. The Black health disadvantage starts at birth, reflecting the cumulative toll of racialized social stressors and healthcare discrimination on maternal health and resulting in higher rates of pre-term birth and low birth weight. Black youth are disproportionately exposed to environmental toxins such as lead and adverse childhood events such as financial hardship and neighborhood violence. Black children also have higher rates of chronic disease, including asthma and diabetes. These and other forces result in inequities in child health and well-being and can also impact children's educational and earning potential. Furthermore, these inequities culminate in a stark racial longevity gap: in Philadelphia, the location of this study, life expectancy for people living in a poor, predominantly Black neighborhood is 20 years lower than for people living in a nearby affluent, predominantly White neighborhood. The fundamental cause of these striking and pervasive disparities is structural racism - the confluence of deep historical, institutional, cultural, and ideological forces that unequally distribute resources and risks across racialized groups. Structural racism patterns health by affecting a range of interconnected, mutually reinforcing social determinants of health at the national, neighborhood, household, and individual levels. Most notably, longstanding, systematic disinvestment has resulted in highly segregated Black neighborhoods with dilapidated environmental conditions and severe economic insecurity within Black households, leading to a "feedback loop of concentrated racial disadvantage," all of which have been strongly tied to poor health. Most interventions seeking to address racial health disparities focus on individual-level behaviors and outcomes, or individual channels by which structural racism harms health. However, by failing to address upstream social determinants, these interventions have had limited population level impact. A multi-level, multi-component intervention package focused on a range of social determinants of health is necessary to meaningfully address structural racism as a fundamental cause of racial health disparities. In this trial, we aim to implement such a multi-level, multi-component intervention and then evaluate its impact on child health and well-being.

Interventions

OTHERAssigned Interventions

Financial well-being interventions: • Tax preparation; access to public benefits; financial counseling and microgrants Place-based interventions: • Vacant lot greening; abandoned house remediation; trash cleanup; tree planting

Sponsors

University of Pennsylvania
Lead SponsorOTHER
Children's Hospital of Philadelphia
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Masking description

The investigators are not masked. Our recruitment team will be masked until cluster recruitment is complete. The outcomes assessor will be masked.

Eligibility

Sex/Gender
ALL
Age
3 Years to 19 Years
Healthy volunteers
No

Inclusion criteria

* Child is between the ages of 3 and 17 years at the start of the trial (between the ages of 5 and 19 years at the end of the trial) * Parent/caregiver is at least 18 years of age * Parent/caregiver has the ability to communicate via text messaging * Parent/caregiver is comfortable communicating in English * Child is a permanent resident of the home where they are to be enrolled * Parent/caregiver has knowledge of their household finances

Exclusion criteria

* Children who plan to move out of the study microcluster within 6 months * Children whose caregivers are unable to fully consent and participate based on CC team assessment

Design outcomes

Primary

MeasureTime frameDescription
Child Health Questionnaire Parent Form 28 (CHQ-PF28) Composite Score24 monthsComposite index using CHQ-28 scoring method, based on a series of 28 questions focused on overall child health, activity limitation, emotional/behavioral difficulties, mood, relationships, and family cohesion. (Child Health Questionnaire)

Secondary

MeasureTime frameDescription
Parent-reported child health24 months(5-pt Likert ranging from poor to excellent) (Child Health Questionnaire)
Caregiver-reported child health care utilization, well child visits24 monthsWell child visits in previous 12 months (National Survey of Children's Health)
Caregiver-reported child health care utilization, sick clinic visits24 monthsSick clinic visits in previous 12 months (National Survey of Children's Health)
Caregiver-reported child health care utilization, emergency room visits24 monthsEmergency room visits in previous 12 months (National Survey of Children's Health)
Caregiver-reported child health care utilization, hospitalization24 monthsHospitalizations in previous 12 months (National Survey of Children's Health)
Forgone health care24 monthsCaregiver report of whether the child needed but did not receive medical, mental health, dental, or vision care in the previous 12 months (National Survey of Children's Health)
Uninsurance or gaps in insurance24 monthsUninsurance or gaps in insurance in the previous 12 months (National Survey of Children's Health)
School attendance24 monthsSchool attendance, based on Philadelphia school district data (Proportion of school days attended, internally developed)
School performance24 monthsSchool performance, based on Philadelphia school district data (Grade point average over previous 12 months, internally developed)
Rate of preterm birth24 monthsRate of preterm birth (birth \< 37 weeks of gestation age), based on Pennsylvania birth certificate data
Rate of low birthweight24 monthsRate of low birthweight (birthweight \<2000 grams), based on Pennsylvania birth certificate data
Health care utilization: emergency room visits in the previous 12mon24 monthsMonthly or quarterly data from 2 years prior to enrollment through approximately 1 year after from HealthShare Exchange
Health care utilization: hospitalizations24 monthsHealth care utilization: hospitalizations in the previous 12 months, based on Children's Hospital of Philadelphia EHR data

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORAtheendar Venkataramani, MD, PhD

University of Pennsylvania

PRINCIPAL_INVESTIGATOREugenia South, MD, MSHP

University of Pennsylvania

PRINCIPAL_INVESTIGATORAditi Vasan, MD, MSHP

Children's Hospital of Philadelphia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 31, 2026