Sepsis
Conditions
Brief summary
We will show in this study the impact of use the rapid diagnostic method (multiplex PCR filmArray) on clinical and pharmacoeconomic aspects among Critically Ill Patients.
Detailed description
Prospective and retrospective study on 100 patients complaining from sepsis in intensive care unit in International Medical center. Two phase study 50 patients before and 50 patients after use rapid diagnostic test (multiplex PCR filmArray)
Interventions
DIAGNOSTIC_TESTrapid diagnostic test (multiplex PCR filmArray)
novel diagnostic platform, the FilmArray®, which combines automated sample preparation, nucleic acid extraction and PCR-based detection of 31 separate targets from a single unprocessed sample in one hour. It combines nesting and multiplexing of the PCR (referred to here as nested multiplex or nmPCR) together with DNA melting curve analysis.
Sponsors
Cairo University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
16 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 85 years * Critically ill patients admitted to ICU, diagnosed as sepsis.
Exclusion criteria
* Surviving time less than 48 hours.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical | through study completion, an average of 1 year | Clinical resolution of sepsis ( by percentage) |
| Pharmacoeconomic | through study completion, an average of 1 year | 1-Reduction of cost and reduction of respective antimicrobial cases (by percentage ) |
| pharmacoeconomic | through study completion, an average of 1 year | DOT of antimicrobial (by days ) |
Contacts
Primary ContactRAED EMAD ALY, MASTER
Backup Contactmohamed amin fakher, M.D
Outcome results
None listed