PreDiabetes
Conditions
Keywords
Prediabetes, Metformin HCl, Apple cider vinegar
Brief summary
The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question\[s\] it aims to answer are: * Efficacy of metformin versus apple cider vinegar in prediabetics * Safety of metformin versus apple cider vinegar in prediabetics Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..
Interventions
DRUGMetformin Hydrochloride (HCL)
Tab Metformin HCL 500mg twice per day aimed at improving glycemic indices in Prediabetics
DIETARY_SUPPLEMENTApple cider vinegar
Apple cider vinegar aimed at improving glycemic indices in Prediabetics
Sponsors
Bahria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Randomized, open label, prospective, clinical trial
Eligibility
Sex/Gender
ALL
Age
17 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Males and Female * 17-40 years age * Body Mass index (BMI) overweight and obese * FBS (100-125 mg/dl) * HBA1c 5.7% to 6.4%
Exclusion criteria
* Concomitant medical problems as established diabetes, hepatic or renal insufficiencies etc. * Known allergy or intolerance to metformin or apple cider vinegar
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycated Hemoglobin | 12 weeks | Change in glycosylated hemoglobin (HbA1c ) in percent |
| Fasting Blood Sugar | 12 weeks | Change in fasting blood sugar (FBS) in mg/dL |
Countries
Pakistan
Outcome results
None listed