Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05756387

Acronym

NOCTIVENT

Enrollment

100

Registered

2023-03-06

Start date

2024-12-01

Completion date

2028-12-01

Last updated

2026-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Respiratory Failure, Non-invasive Ventilation

Keywords

Monitoring

Brief summary

The aim of the data collection is to create an advanced reliable method to remotely monitor patient on chronic home non-invasive ventilation (NIV), both regarding ventilatory efficacy and patient comfort, both in the hospital and at home by assessing gas exchange, lung mechanics and the interaction between the patient and the ventilator. For this purpose, we will set-up of databank of synchronously acquired datasets of already standard care monitored parameters during NIV (transcutaneous monitoring of gas exchange; ventilator data including data on PVA), and newly non-invasively acquired data on patient effort (EMG, patient ratings) and lung (hyper)inflation (EIT), during the set-up and follow-up of standard care chronic NIV.

Detailed description

Can be provided on request as the registry rules are no in Dutch

Interventions

DEVICENon-invasive ventilation

NIV as in standard care

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* COPD patients indicated for chronic home NIV

Exclusion criteria

* not able to read the written information and/or sign the informed consent form * no possibility to perfrom measurements at home

Design outcomes

Primary

Measure	Time frame	Description
Gas exchange	baseline	Transcutaneous monitoring of gas exchange
Patient comfort	baseline	Patient comfort assessed by VAS scale
AECOPD	2 months, 4 months, 6 months	Acute exacerbations of COPD (defines as deterioration of symptoms requiring a course of/increase in Prednisolone dose and/or antibiotics)
Hospitalisations for AECOPD	6 months	Hospitalisations for acute exacerbations of COPD
Sleep quality	2 months	Sleep quality assessing sleep depth and sleep stages

Countries

Netherlands

Contacts

CONTACTMarieke L Duiverman, MD PhD

m.l.duiverman@umcg.nl0031503613200

PRINCIPAL_INVESTIGATORMarieke L Duiverman

University Medical Center Groningen

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 3, 2026