ART, Infertility, Female
Conditions
Keywords
embryo quality, LH levels, Oocyte retrieval
Brief summary
Luteinizing hormone (LH) plays a key role for normal follicular development and oocyte maturation in controlled ovarian stimulation. In particular, LH stimulates the proliferation and differentiation of theca cells for the secretion of androgens, which synergistically increase the production of estrogen. This study aimed to investigate the effects of low LH concentrations on oocyte retrieval, fertilization and embryo development in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). Patients undergoing IVF/ICSI were prospectively analyzed, subdividing them into three groups according to their age. Serum LH levels were evaluated at day 3, during stimulation (day 10) and before ovulation induction (day 12).
Interventions
None listed
Sponsors
University of Palermo
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
age between 18 and 40 years, body mass index 18-29 kg/m 2 , regular menstrual cycles, normal uterine cavity assess by hysteroscopy, normal uterus and ovaries at transvaginal sonography,
Exclusion criteria
abnormal cervical cytology, affected by any other endocrinological, metabolic, autoimmune, and gynecological disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oocyte retrieval | immediately after the intervention | number of retrieved oocytes after controlled ovarian stimulation |
Contacts
Primary ContactAndrea Etrusco, M.D.
Outcome results
None listed