The Effects of MLS LASER Therapy in Patients With Chronic Nonspecific Neck Pain

Pilot Study on the Effects of MLS (Multiwave Locked System) LASER Therapy in Patients With Chronic Nonspecific Neck Pain: Randomized Controlled Trial Versus Placebo

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05753540

Enrollment

Registered

2023-03-03

Start date

2022-03-21

Completion date

2023-03-31

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Non-specific Neck Pain

Brief summary

Non-specific cronic low back pain is very common condition affecting 30-50% of adults. It is featured by neck muscles contractures which lead to pain and reduction of cervical spine mobility. High intensity laser therapy has been shown to be an effective treatment to improve symothoms in patient with non-specific neck pain. The aim of this study is to assess the effects of a multi-wave locked system laser therapy in patient with non-specif neck pain.

Interventions

OTHERLaser therapy

Multiwave locked system laser therapy

OTHERSham laser therapy

Sham laser therapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Chronic low back pain (\> 3 months) * Body mass index \< 30 * Preserved cognitive ability to fully understand and observe indications received by medical personnel * Ability to understand and give an informed consent

Exclusion criteria

* Spine surgery * Spinal hernia * spondylolisthesis * Spinal infections * Severe spine deformities * Neural diseases * Upper limbs radiculopathy * Cervical rib * Rotator cuff or other shoulder diseases * Rheumatic diseases * Diabetes * Psychiatric diseases * Vascular diseases * Cancer * Infectious diseases * Skin abrasion * Pregnancy or breastfeeding * Recent injuries * Known sensibility to Laser therapy * Epilepsy * Anticoagulant therapy * Pacemaker * hemorrhagic diathesis * Photosensitizing drugs * Known Photosensibility * Neck Tattoos

Design outcomes

Primary

Measure	Time frame	Description
Change in Neck pain	Change from baseline neck pain at 3 and 7 weeks	Eleven point (0-10) visual analogue scale

Secondary

Measure	Time frame	Description
Change in Disability	Change from baseline disability at 3 and 7 weeks	Neck disability index questionnaire

Other

Measure	Time frame	Description
Change in Neck mobility	Change from baseline neck mobility at 3 and 7 weeks	Degree of head rigth/left flexion, forward/backward flexion and rigth/left rotation, together with the velocity of the movements measured with an accelerometer

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026