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Impact of Conventional Treatments and Clinical Variables on Thyroid Cancer

Retrospective and Prospective Evaluation of the Impact of Innovative and Conventional Treatments and of Clinical Variables on the Outcome of Thyroid Cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05752604
Acronym
THY-CANC
Enrollment
3000
Registered
2023-03-02
Start date
2022-07-12
Completion date
2042-03-08
Last updated
2025-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Brief summary

DTC has a generally favorable prognosis. The possibility to discriminate between patients with aggressive tumors and those with a more indolent behavior may reduce the need for unnecessary treatments. Aim of this observational study is to evaluate how anamnestic, clinical, and histopathological variables may influence the outcome of the enrolled patients, both regarding morbidity and mortality and in terms of therapeutic choices. The study aims to evaluate the prognostic impact of the therapeutic interventions in terms of efficacy and regarding the appearance of adverse events.

Interventions

None listed

Sponsors

Istituto Auxologico Italiano
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

\- thyroid cancer diagnosis

Exclusion criteria

* patients unable to sign informed consent

Design outcomes

Primary

MeasureTime frameDescription
Dynamic risk stratificationone year from the primary treatmentimpact of the different variables on the DRS
Progression-free survivalone year from the primary treatmentimpact of the different variables on the PFS in patients treated with TKI for advanced thyroid cancer
Overall survivalone year from the primary treatmentimpact of the different variables on the OS in patients treated with TKI for advanced thyroid cancer

Countries

Italy

Contacts

Primary ContactLaura Fugazzola, MD
l.fugazzola@auxologico.it+390261911

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026