Pulmonary Rehabilitation
Conditions
Brief summary
The primary aim of this pilot randomized controlled trial is to determine feasibility of the proposed pulmonary rehabilitation intervention.
Detailed description
In this pilot randomized controlled trial, our primary aim is to determine feasibility of the proposed intervention.
Interventions
DEVICEHigh flow oxygen
Use of HFO
OTHERUsual care
Room air or normal flow oxygen
Sponsors
Changi General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* 21 years and above * Presence of exertional hypoxemia during 1-minute sit-to-stand test * diagnosis of acute COPD exacerbation or Covid-19 pneumonia or exacerbation of bronchiectasis or exacerbation of interstitial lung disease * physically fit to participate in exercise therapy as determined by both the patient's physician and physiotherapist
Exclusion criteria
* uncontrolled severe medical conditions * currently enrolled in a pulmonary rehabilitation trial * unsuitable for randomization as determined by the patient's physician
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in 1-minute sit to stand test | 1 month | maximum number of sit to stand cycles in 1 minute |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in 30-second sit to stand test | 1 month, 3 month | maximum number of sit to stand cycles in 30 seconds |
| Changes in respiratory symptoms | 1 month, 3 months | Modified Medical Research Council Dyspnea Scale. The scale ranges from 0 to 4 with a higher score indicating increasing breathlessness |
| Changes in mood | 1 month, 3 month | Hospital Anxiety Depression Scale. The scale ranges from 0 to 21, A total subscale score of \>8 points indicates considerable symptoms of anxiety or depression. |
| changes in quality of life | 1 month, 3 month | EQ-5D-5L |
| Proportion of patients who still have exertional hypoxemia | 1 month, 3 month | Comparing the proportion of patients who still have exertional hypoxemia |
| Adherence rates | 3 week | Comparing the adherence rates between the 2 study arms |
| Changes in 1-minute sit to stand test | 3 month | maximum number of sit to stand cycles in 1 minute |
| Changes in lung function | 1 month, 3 month | Forced expiratory volume in 1 sec |
Other
| Measure | Time frame | Description |
|---|---|---|
| Qualitative interview | Upon completion of study, or when patients end participation in the study | Qualitative interviews will also be conducted to obtain patient perspectives of the interventions in the study |
Countries
Singapore
Contacts
Primary ContactYingjuan Mok, MBBS
Outcome results
None listed