Analysis of the Persistence, Reservoir and HIV Latency

APRIL Study: Analysis of the Persistence, Reservoir and HIV Latency

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05752318

Acronym

APRIL

Enrollment

500

Registered

2023-03-02

Start date

2023-02-27

Completion date

2027-02-25

Last updated

2023-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV Infected Individuals, Informed Consent

Keywords

HIV, Reservoir, Latency, Persistence

Brief summary

The APRIL study aims at analyzing HIV reservoirs, latency and persistence on antiretroviral therapy. It enrolls HIV-infected adults providing blood samples of which peripheral blood mononuclear cells are stored. The frequency, phenotype and inducibility of HIV-infected cells are then analyzed. These parameters may vary across the different clinical and therapeutic settings.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* HIV-infection * Adults (\>18 years) * Social insurance * Informed consent

Exclusion criteria

* HIV-uninfected * \<18 years * Lack of social insurance * Lack or withdraw of consent

Design outcomes

Primary

Measure	Time frame
HIV-Flow	1 day

Contacts

Primary ContactPierre GANTNER, MCU-PH

pierre.gantner@chru-strasbourg.fr03 69 55 16 32

Outcome results