Bone Fracture
Conditions
Brief summary
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
Interventions
DRUGDexmedetomidine
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg Dexametomidine.
DRUGKetamine
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
-The study will include 100 adult patients (18 to 50 years old) with ASA physical status class I and class II undergoing orthopedic lower limb surgeries under itrathecal anathesia .
Exclusion criteria
* Patient refusal. * Drug abuse. * Patient with neurological, psychiatric or neuromuscular disease. * Chronic pain on medicine. * Known allergy to the study medications. * Patients e contraindications to intrathecal anesthesia .
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery | 1 year | comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery. |
Countries
Egypt
Contacts
Primary Contactzeyad A Ali, Resident
Backup ContactAhmed E Abd Elrahman, Professor
Outcome results
None listed