Type A Aortic Dissection
Conditions
Keywords
Type A Aortic Dissection
Brief summary
This is a retrospective study based on the data available in our hospital database for ATAAD patients from January 2020 to December 2021. These patients were divided into two groups according to the surgical procedures of aortic root. This study compared baseline data, perioperative and short-term follow-up results between the two groups to evaluate the efficacy and safety of XJ-procedure in ATAAD.
Detailed description
Acute type A aortic dissection (ATAAD) is a life-threatening disease with high mortality. Surgery remains the gold standard for the treatment of ATAAD. In recent years, ATAAD is still a persistent challenge for cardiovascular surgeons. This is a retrospective study based on the data available in our hospital database for ATAAD patients undergoing total aortic arch replacement with elephant trunk stent under cryogenic stop circulation from January 2020 to December 2021. These patients were divided into two groups according to the surgical procedures of aortic root: continuous aortic root suture group (CARS group); aortic root reinforcement combined with vascular grafts eversion and built-in, which was created by our group and to be named as XJ-procedure (XJ-procedure group, XJ is an acronym for Xi'an Jiaotong University). The main outcome was defined as 30-day mortality. Secondary outcomes included the postoperative bleeding necessitating re-operation and the incidence of anastomotic pseudoaneurysm, residual aortic root dissection and severe aortic regurgitation before discharge and at 3 and 6 months after the operation. This study compared baseline data, perioperative and short-term follow-up results between the two groups to evaluate the efficacy and safety of XJ-procedure in ATAAD.
Interventions
OTHERNo Intervention.
No Intervention.
Sponsors
First Affiliated Hospital Xi'an Jiaotong University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diagnosed with ATAAD by computed tomography angiography (CTA) from January 2020 to December 2021 in the First Affiliated Hospital of Xi'an Jiaotong University * Mild to moderate aortic root involvement * Aortic arch involvement undergoing Sun's procedure
Exclusion criteria
* Patients with severe aortic root involvement (root diameter \>45 mm, root tear, severe disruption of aortic root, concomitant valve disease) * The Bentall, Wheat or David procedure performed * Recurrent ATAAD * Preoperative severe brain complications (cerebral infarction, cerebral hemorrhage, coma, etc.) * Mal-perfusion of abdominal organs or lower extremities \>12 h * Incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 30-day mortality | Within 30 days after the surgery | Patients died within 30 days after the surgery. Data were obtained from the medical records. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The postoperative bleeding necessitating re-operation | About 2 weeks after the surgery. | Postoperative bleeding necessitated reoperation during hospitalization. Data were obtained from the surgical records and medical records. |
| Change in the incidence of anastomotic pseudoaneurysm | About 2 weeks after surgery, 3-month and 6-month follow-up. | The occurrence of anastomotic pseudoaneurysm was examined by postoperative computed tomography angiography examination. |
| Change in the incidence of residual aortic root dissection | About 2 weeks after surgery, 3-month and 6-month follow-up. | The occurrence of residual aortic dissection was examined by postoperative computed tomography angiography examination. |
| Change in the incidence of severe aortic regurgitation | About 2 weeks after surgery, 3-month and 6-month follow-up. | The occurrence of aortic valve regurgitation greater than grade2+, which was decided by cardiac ultrasonography. |
Countries
China
Outcome results
None listed