Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcomes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05750927

Acronym

ASCOP

Enrollment

100

Registered

2023-03-02

Start date

2022-12-01

Completion date

2023-12-31

Last updated

2024-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angioplasty, Balloon, Coronary, Aortic Valve Stenosis, Coronary Artery Disease, Transcatheter Aortic Valve Replacement

Brief summary

To describe the prevalence and clinical features of patients with severe aortic stenosis undergoing TAVI and concomitant clinically indicated, complex and/or high-risk PCI

Detailed description

The aims of this study are: * to describe the prevalence and clinical features of patients with severe aortic stenosis undergoing TAVI and concomitant clinically indicated, complex and/or high-risk PCI * to depict the different possible strategies that are currently employed in this context and to retrospectively analyze outcomes * to investigate predictors of better outcomes

Interventions

PROCEDURETranscatheter aortic valve intervention (TAVI) and percutaneous coronary intervention (PCI)

TAVI and PCI to be administered as per physician's indication and choice, in one or more stages

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

1. Severe, symptomatic aortic stenosis with an indication to TAVI 2. Concomitant, stable CAD with an indication to complex PCI, as anticipated by angiography, defined as follows (one or more features) 1. Left-main (LM) CAD or proximal left anterior descending (LAD) / left circumflex (LCx) lesions requiring LM-PCI 2. Three-vessel disease 3. Last remaining vessel 4. Bifurcation PCI (proximal bifurcation) 5. Severely calcified lesions requiring calcium plaque modification (rotational/orbital atherectomy, intravascular lithotripsy, scoring or cutting balloon) 6. Lesion length \> 30 mm 7. Severely depressed Left ventricular function requiring mechanical circulatory support (intra-aortic balloon pump - IABP, Impella, Extracorporeal Membrane Oxygenation - ECMO

Design outcomes

Primary

Measure	Time frame	Description
POCE	1 year	all-cause deaths, strokes (any), myocardial infarction and major bleedings

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026