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The Nationwide Real-world Status of Oral Corticosteroid Use in Patients With Asthma

The Nationwide Real-world Status of Oral Corticosteroid Use in Patients With Asthma

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05750797
Enrollment
800000
Registered
2023-03-02
Start date
2023-03-01
Completion date
2023-12-31
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma, Corticosteroid

Brief summary

The Health Insurance Review and Assessment Service (HIRA) database contains nationwide claim data. By utilizing this database, the investigators aimed to analyze the current status of OCS use in South Korea by using HIRA database.

Detailed description

South Korea has a compulsory universal health insurance system for entire Korean population. The number of people who are covered was more than 50 million. The Health Insurance Review and Assessment Service (HIRA) database contains nationwide claim data. By utilizing this database, the investigators have performed many studies regarding asthma in South Korea. In this study, the investigators aimed to analyze the current status of OCS use in South Korea by using HIRA database. Primary outcome was the OCS prescription in all patients with asthma. Secondary outcome was OCS prescription according to the asthma severity, age, sex, socioeconomic status and the type of hospital. Inclusion criteria was 1) Age ≥ 15 years; 2) ICD-10 codes for asthma (J45.x-J46) as the primary or within fourth secondary diagnosis; 3) use of more than one drug for asthma at least twice per year (long acting muscarinic antagonist (LAMA), long acting beta2 agonist (LABA), ICS, ICS+LABA, short acting muscarinic antagonist (SAMA), short acting beta2 agonist (SABA), SAMA+SABA, theophylline, leukotriene antagonist, systemic corticosteroids, or systemic beta agonist).

Interventions

The prescription of OCS will be analyzed. OCS included betamethasone, deflazacort, dexamethasone, hydrocortisone, methylprednisolone, prednisolone, and triamcinolone.

Sponsors

Seoul St. Mary's Hospital
CollaboratorOTHER
Hallym University Medical Center
CollaboratorOTHER
Konkuk University Hospital
CollaboratorOTHER
Joon Young Choi
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age ≥ 15 years; * ICD-10 codes for asthma (J45.x-J46) as the primary or within fourth secondary diagnosis * use of more than one drug for asthma at least twice per year (long acting muscarinic antagonist (LAMA), long acting beta2 agonist (LABA), ICS, ICS+LABA, short acting muscarinic antagonist (SAMA), short acting beta2 agonist (SABA), SAMA+SABA, theophylline, leukotriene antagonist, systemic corticosteroids, or systemic beta agonist).

Exclusion criteria

• Those who are not in the insurance system

Design outcomes

Primary

MeasureTime frameDescription
OCS prescription rates1-yearAnalysis the OCS prescription in all patients with asthma

Secondary

MeasureTime frame
OCS prescription according to the asthma severity1-year
OCS prescription according to age1-year
OCS prescription according to sex1-year
OCS prescription according to socioeconomic status1-year
OCS prescription according to the type of hospital1-year

Countries

South Korea

Contacts

Primary ContactJoon Young Choi, MD.PhD
tawoe@naver.com82 10 5313 2937

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026