Acute Lymphoblastic Leukemia, Adult, Invasive Fungal Infections
Conditions
Brief summary
The study aims to evaluate incidence of invasive antifungal infections among patients with acute lymphoblastic leukemia Ph negative during the first weeks of treatment
Interventions
OTHERobservation of invasive fungal infections
observation of invasive fungal infections during chemotherapy
Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Asst Degli Spedali Civili Di Brescia
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Campus Bio-Medico University
Azienda Sanitaria Universitaria Friuli Centrale
San Gallicano Dermatological Institute IRCCS
University of Rome Tor Vergata
University of Modena and Reggio Emilia
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Vito Fazzi Hospital
Azienda Ospedaliera di Padova
San Raffaele University Hospital, Italy
Azienda Ospedaliera Universitaria Integrata Verona
Azienda Ospedaliero-Universitaria di Parma
Azienda Ospedaliera "Sant'Andrea"
S.Eugenio Hospital
San Giovanni Addolorata Hospital
Casa Sollievo della Sofferenza-IRCCS, San Giovanni Rotondo
ASST Sette Laghi
Ospedale San Bortolo di Vicenza
Fondazione IRCCS Policlinico San Matteo di Pavia
A.O.U. Città della Salute e della Scienza
Istituto Oncologico Veneto IRCCS
Azienda Ospedaliera San Gerardo di Monza
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* diagnosis of acute lymphoblastic leukemia Ph negative * age more than 18 yo
Exclusion criteria
* diagnosis of acute lymphoblastic leukemia Ph positive * acute lymphoblastic leukemia relapsed/refractory * lymphoblastic lymphoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of invasive fungal infections | 18 months | Incidence of invasive fungal infections during first week of chemotherapy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality rate | 30 months | Mortality rate among patients with invasive fungal infections |
Countries
Italy
Contacts
PRINCIPAL_INVESTIGATORMarianna Criscuolo
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Outcome results
None listed