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Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome

The Effect of Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Healthcare Workers With Burnout Syndrome

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05750160
Enrollment
30
Registered
2023-03-01
Start date
2023-02-13
Completion date
2023-03-18
Last updated
2023-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burnout Syndrome, Interleukin-10, Interleukin-6, Neutrophil-Lymphocyte Ratio

Brief summary

Burnout Syndrome (BOS) can be defined as a state of stress both physically and psychically due to the burden and stressor of high work. The prevalence of BOS in health workers varies between 25-75% globally. Studies have shown that the presence of Burnout syndrome will meaningfully reduce the quality of services related to patient safety and cause immune system disorders that act as the body's defense against viral, bacterial, protozoal and fungal infections. Many strategies have been researched to help prevent and reduce the occurrence of Burnout syndrome, one of which is music therapy. The purpose of this study was to determine the effect of music therapy on the immune response in health workers with Burnout Syndrome. This study is a randomized clinical trial with a pre and post test control group design for health workers at Dr Kariadi General Hospital and Dr. Cipto Mangunkusumo General Hospital. Subjects will be provided with information prior to the study and asked to sign an informed consent sheet if they agree to be involved in the study. Subjects will be divided into control groups and treatment groups with matching age, gender and type of work. In the treatment group, music therapy will be given as much as 3 times a week for 4 weeks. Data were taken on both groups before and after the intervention. This study used the Maslach Burnout Inventory Human Service Survey (MBI-HSS) and blood laboratory examination to determine the value of the Neutrophyl Lymphocyte Ratio, Interleukin 6 and Interleukin 10 levels.

Interventions

OTHERmusic therapy

Music therapy that have been made by Music Therapist after Focus Group discussion, given three times a week for 4 weeks

Sponsors

Indonesia University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

1. Age 18 years - 60 years old 2. Health workers in the wards and polyclinic of Dr. Cipto Mangunkusumo Hospital or Dr. Kariadi Hospital, including doctors in charge of patients, nurses, residents, and other supporting health workers 3. Included in the Burnout syndrome criteria from the Maslach Burnout Inventory-Human Service Survey questionnaire

Exclusion criteria

1. Refusing to follow the study 2. Have a history of heart disease, kidney disease, diabetes, cancer, tuberkulosis, autoimmune, immunodeficiency 3. Taking drugs that affect the central nervous system or immunosuppressants 4. Have hearing disorder 5. Have a psychiatric disorder 6. Being pregnant 7. Healthcare workers who don't like music

Design outcomes

Primary

MeasureTime frameDescription
Burnout syndromechange from baseline score at 4 weeksMaslach Burnout Inventory Human Service Survey (MBI-HSS) score
Neutrophil Lymphocyte RatioChange from baseline Neutrophil Lymphocyte Ratio at 4 weeksMeasured with Fluorescence Flow Cytometry
Interleukin 6Change from baseline Interleukin-6 level at 4 weeksMeasured with Fluorescence Immunoassay
Interleukin 10Change from baseline Interleukin-10 level at 4 weeksMeasured with ELISA

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026