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Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia

Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05749978
Enrollment
60
Registered
2023-03-01
Start date
2023-01-01
Completion date
2024-12-30
Last updated
2023-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asana Adjustment

Keywords

Trendelenburg position, Prone Position, Hemodynamics, Intra-abdominal pressure, Cardiac output

Brief summary

The prone position is a special position often used for spinal surgery. As a special position of general anesthesia, after induction of general anesthesia, severe hemodynamic fluctuations often occur when the supine position is changed to the prone position, which seriously affects the patient's circulatory and respiratory functions.

Interventions

BEHAVIORALAsana adjustment

Adjust the operating table to 15° head height and foot low in advance. The patient is then slowly turned over from the transport table to the operating table and completed in the prone position. After the patient's hemodynamic stability is smooth, adjust the operating table to the level.

Sponsors

Zhuan Zhang
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

1. Prone spine surgery after general anesthesia is planned. 2. Age 18\ 85 years old. 3. ASA grade I or II. 4. BMI18.3-30kg/m2

Exclusion criteria

1. Unstable angina or myocardial infarction, coronary heart disease, congestive heart failure, structural heart disease, arrhythmia within 6 months; 2. Increased intracranial pressure and central nervous system injury or disease; 3. Severe hypertension 4. Patients with other diseases affecting their own circulatory system. 5. Have or have a history of severe mental disorders; 6. Bleeding volume \>600ml or intraoperative blood transfusion treatment. 7. Severe liver and kidney insufficiency

Design outcomes

Primary

MeasureTime frameDescription
Change in Blood pressurePreoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone positionHemodynamics
Changes in the level of Cardiac outputPreoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone positionCardiac output

Secondary

MeasureTime frameDescription
Intra-abdominal pressure levelPreoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone positionIntra-abdominal pressure
Vasoactive drugsIntraoperativelyVasoactive drug dosage

Countries

China

Contacts

Primary ContactZhuan Zhang
zhangzhuancg@163.com+8615062791355

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026