Hiccup
Conditions
Keywords
hiccup
Brief summary
Hiccup is a common symptom, and it is currently believed that hiccups result from diaphragmatic spasm, with onset ranging from minutes to days. Some patients may terminate on their own, or by ways such as gasping. For some patients with duration longer than 1 day, even longer than 2 days, medications may be needed, mainly: metoclopramide, eperisone hydrochloride tablets, etc. Acupuncture is also effective for some patients. Surgical treatment may be required for some clinically intractable hiccups. However, for the above interventions or treatment means, the current efficacy still needs to be improved. In the previous clinical experience, we create a new physical clinic protocol which could terminate the hiccup symptom onset instantaneously without adding extra cost to the patient, and the physiotherapy method was convenient and effective. To further validate the superiority, safety of this novel physical therapy regimen, we designed a randomised controlled, prospective, single centre clinical study aimed at comparing the efficacy and safety of the novel physical therapy with conventional pharmacotherapy in patients with hiccups.
Interventions
BEHAVIORALphysiotherapy
New physical therapy: a disposable cup (soft cup) to take 1/3 cup of room temperature water and place it on a table. The patient takes a sitting or standing position. The middle finger of both hands press tightly against the nose to seal the nasal cavity. At the same time, press the ear screen with both hands to close the ear canal. After that, bite the cup with teeth (hands do not touch the cup), and drink up 1-2 mouthfuls of water.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age ≥ 18 years * Able to swallow water
Exclusion criteria
* Allergy or contraindication to the following drugs: metoclopramide et al * Severe choking on water and difficulty swallowing were present * Impaired consciousness and inability to cooperate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the rate of termination of hiccup in 30 seconds | 1 year | the rate of termination of hiccup in 30 seconds |
| the time course from the start of therapy to the end of hicuup | 1 year | the time course from the start of therapy to the end of hicuup |
Countries
China
Contacts
Primary ContactShen Jian
Outcome results
None listed