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Different Surgical Approaches for Treatment of UPJ Obstruction in Children: Prospective Randomized Clinical Trial

Different Surgical Approaches for Treatment of UPJ Obstruction in Children: Prospective Randomized Clinical Trial

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05748964
Enrollment
20
Registered
2023-03-01
Start date
2023-04-01
Completion date
2025-06-01
Last updated
2023-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery, Urologic Diseases

Keywords

UPJ obstruction, pediatric urology, pyeloplasty

Brief summary

This study aimed to evaluate the clinical efficacy of laparoscopic pyeloplasty (LP) for ureteropelvic junction obstruction (UPJO) via retroperitoneal and transperitoneal approaches.

Detailed description

Ureteropelvic junction obstruction (UPJO) is the most common congenital abnormality of the kidney and is responsible for flank pain, recurrent urinary infections, hydronephrosis and the loss of renal function. Until recently, open pyeloplasty (OP) was the standard surgical treatment modality for UPJO.However, with the development of laparoscopic devices and surgical technology, laparoscopic pyeloplasty (LP) has become a more beneficial choice for the patients with UPJO than open surgery because of the advantages of excellent visualization, minimal trauma, rapid postoperative recovery, good cosmetic result, and a nearly successful rate compared with open pyeloplasty. The first LP in children was performed in 1995. It has gained popularity for older children. LP can be performed though retroperitoneal and transperitoneal approaches. Which surgical method is better is still controversial.

Interventions

Twenty patients presented with ureteropelvic junction obstruction \[UPJO\] will be divided into two equal groups. The first was subjected to trans-peritoneal pyeloplasty while the second was subjected to retroperitoneal pyeloplasty.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
2 Years to 18 Years

Inclusion criteria

* Age above two years. * Unilateral UPJO.

Exclusion criteria

* Age below two years. * Bilateral UPJO. * Recurrent UPJO. * Malrotated kidneys and renal fusion anomalies.

Design outcomes

Primary

MeasureTime frameDescription
Operative timeFrom April 1, 2023 to April 1, 2024Operative time

Secondary

MeasureTime frameDescription
Convergence rateFrom April 1, 2023 to April 1, 2024Convergence to open pyeloplasty
Post operative complicationsFrom April 1, 2023 to April 1, 2024Post operative complications
Hospital stayFrom April 1, 2023 to April 1, 2024Hospital stay

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026