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Evaluation of Morphology Abnormal Cornea Stability With Corneal Biomechanical

Prediction for Abnormal Topography Corneas Using New Biomechanical Parameter - Biomechanical Stable Index

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05748002
Enrollment
315
Registered
2023-02-28
Start date
2018-07-16
Completion date
2022-12-01
Last updated
2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus, Stable

Brief summary

To evaluate the corneal biomechanical properties of stable eyes with abnormal morphology, and introduce a biomechanical stable index to evaluate the stability of the eyes with abnormal morphology at the first diagnosis.

Interventions

OTHERPentacam and Corvis ST

morphological and biomechanical parameters of corneal were obtain by Pentacam and Corvis ST

Sponsors

Tianjin Eye Hospital
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

1. Best corrected visual acuity (BCVA) ≥ 20/20; 2. No other eye diseases except myopia and astigmatism; 3. The cornea was transparent, and there was no cloud or pannus; 4. No clinical manifestation of keratoconus(Corneal stromal thinning, Cone-shaped anterior protrusions, Fleischers ring, Vogts striae, Epithelial or subepithelial scarring)

Exclusion criteria

1) corneal disease; 2\) ocular trauma; 3) Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination; 4) Pregnant and lactating women;

Design outcomes

Primary

MeasureTime frameDescription
stableone yearNo alterations in morphological(Pentacam parameters, BAD\<0.42, TCT\<10μm) and biomechanical(Corvis ST, parametersCBI\<0.2, SPA1\<10) parameters between the first and last follow-up.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026