Genetic Disease, Obesity, Childhood
Conditions
Brief summary
This study collects data on children with severe, early-onset obesity.
Detailed description
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children are asked to participate in a prospective, observational study. The investigators collect demographic information, body measurements, medical/family history, as well as other questionnaires. Additionally, genetic information, medical lab results, and responses to treatment options are collected. The goal of the study is to determine if the investigators can better understand which children would benefit from testing and further workup as well as to understand how obesity develops in these children and adolescents.
Interventions
None listed
Sponsors
Baylor College of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* For individuals 2 years and older, BMI \> 97 percentile * For individuals \< 2 years old, weight-to-length ratio \> 95th percentile
Exclusion criteria
* No other
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of genetic causes of severe, early-onset obesity | through study completion, an average of 10 years | We will measure the number of genetic variants identified in clinical testing |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in BMI over time | through participant completion, an average of 2 years | BMI in kg/m2 will be documented over time. BMI is calculated using weight and height |
Countries
United States
Contacts
CONTACTStephanie Sisley, MD
Outcome results
None listed