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The Effects of High vs. Low Time Spent Near VO2max During Two Work-matched High Intensity Interval Training.

The Effects of High vs. Low Time Spent Near VO2max During Two Work-matched High Intensity Interval Training.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05742542
Enrollment
15
Registered
2023-02-24
Start date
2021-07-01
Completion date
2021-12-15
Last updated
2023-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

VO2max

Keywords

VO2max, Exercise, Aerobic, Performance, Training

Brief summary

Maximal oxygen uptake (VO2max) is used to define cardiorespiratory fitness, which is important to health and sport performance in humans. Although different types of training can improve VO2max, the high intensity interval training is recognized as one of the best ways to do it. Furthermore, it has long been speculated that high intensity interval training that elicits a high time spent near VO2max could be the best way to improve VO2max. However, this theory has not been verified. Thus, the investigators performed a randomized controlled trial with crossover in healthy individuals who underwent two high intensity interval training protocols of two weeks, being a workout with longer and other with shorter time spent near VO2max.

Detailed description

Fifteen participants were enrolled in a randomized trial with crossover to perform two weeks of high intensity interval training with high (i.e., five times 2 minutes of work and 1 minute of recovery; T-2min:1min) or low (i.e., ten times 1 minutes of work and 30 seconds of recovery; T-1min:30seg) time spent near VO2max. The work intensity was adjusted at 85% and 87% of power output achieved at the end of incremental test for the first and second week, respectively. Before and after the T-2min:1min and T-1min:30seg, the participants performed tests to determine VO2max, lactate threshold, muscle oxidative capacity, pulmonary oxygen uptake kinetics, power output achieved at the end of incremental test, and power output related to Wingate anaerobic test. The training programs had a washout period of at least one month.

Interventions

OTHERExercise training

Two weeks of high intensity interval training with high or low time spent near VO2max.

Sponsors

University of the State of Santa Catarina
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Intervention model description

The order of training protocols was randomized and the training programs had a washout period of at least one month.

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Male ≥ 18 years; * No known musculoskeletal disorders; * Apparently healthy * Physically active according to American College of Sports Medicine standards and recommendations (Garber et al., 2011; RIEBE et al., 2015).

Exclusion criteria

* Taking any medication that could affect aerobic parameters; * Smokers; * Involved in an aerobic training program at the start of the study.

Design outcomes

Primary

MeasureTime frameDescription
Maximal oxygen uptakeChange at Maximal oxygen uptake after two weeksThe highest 15 seconds VO2 average determined from rolling averages of 5 seconds samples measured during incremental test or confirmation test of VO2max.

Secondary

MeasureTime frameDescription
Muscle oxidative capacityChange at Muscle oxidative capacity after two weeksRate recovery of muscle oxygen consumption (k-mV̇O2) of the vastus lateralis, with the k-mV̇O2 indicating muscle oxidative capacity.
Lactate thresholdChange at Lactate threshold after two weeksThe work intensity at which blood lactate concentration increased 1 mmol.L-1 above baseline.
Pulmonary oxygen uptake kineticsChange at Pulmonary oxygen uptake kinetics after two weeksThe on-transient response for V̇O2 was fitted using a mono-exponential model, which the rate constant (k-pV̇O2) for the kinetics of V̇O2 was calculated as 1/tau (expressed in min-1).
Power output achieved at the end of incremental testChange at Power output achieved at the end of incremental test after two weeksPower output achieved at the end of ramp incremental test (20 W.min-1).
Wingate anaerobic testChange at Wingate anaerobic test after two weeksPeak power, mean power, and minimum power were defined as the highest mechanical power output, the average power sustained throughout the 30-s period, and the power output attained before the end of the test, respectively.
Time spent near VO2maxFirst to the last day of test or training, an average of 4 weeksTime spent at or above 90% or 95% of VO2max.

Other

MeasureTime frameDescription
Heart rateFirst to the last day of test or training, an average of 4 weeksMeasured before and during exercise and used to determine 1) the highest heart rate, 2) the time spent near highest heart rate, 3) training impulse, and 4) heart rate variability.
Adipose tissue thicknessChange at Adipose tissue thickness after two weeksAdipose tissue thickness measured by a B-mode ultrasound imaging.
Body massChange at Body mass after two weeksBody mass measured by a digital scale.
Perceived Recovery Status ScaleFirst to the last day of test or training, an average of 4 weeksThe original 10-point version from Laurent et al (2011).
Session-rating of perceived exertionFirst to the last day of test or training, an average of 4 weeksThe original 10-point version.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026