Neonatal Infection Surveillance Database

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05742490

Acronym

neonIN

Enrollment

12000

Registered

2023-02-24

Start date

2013-12-16

Completion date

2028-11-22

Last updated

2023-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal Infection

Brief summary

NeonIN is a is a neonatal infection surveillance database which will facilitate active surveillance for bacterial infections through a network of neonatal units, using standardised definitions, proformas and microbiological techniques. The centralised and secure web-based database will allow real-time entry of data and rapid and timely analysis of results.

Detailed description

The neonIN surveillance network captures data on episodes of invasive neonatal infection on a web-based database (www.neonin.org.uk). Over 25 UK neonatal units currently contribute to this database in real-time. An episode of neonatal infection is defined as a positive culture collected from a normally sterile site such as the blood, cerebrospinal fluid (CSF) or urine (via catheter or suprapubic aspirate) for which clinicians prescribed at least five days of appropriate antibiotics. Clinical, demographic and microbiological data (including antimicrobial susceptibilities) are collected using a standardised online questionnaire, and denominator data regarding the total number of live-births and neonatal-admissions are collected for each neonatal unit.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Minutes to 12 Months

Inclusion criteria

* Infants on participating Neonatal Units who have an episode of infection with a positive culture

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Incidence of infection	6 months	Collection of neonIN data on episodes of significant neonatal bacterial infections in NNUs recruiting to neonIN
Antibiotic susceptibility	6 months	Collection of neonIN data on susceptibility profiles of significant neonatal bacterial infections
Features of bacterial infections	6 months	Collection of neonIN data on gestation, birth weight, age of onset, clinical presentation and prior antibiotic use of significant neonatal bacterial infections

Countries

United Kingdom

Contacts

Primary ContactSana Ibrahim, BSc

sibrahim@sgul.ac.uk+44 (0)208 725 5382

Outcome results