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Low Grade Serous Ovarian Carcinoma and Uterine Involvement : Should Hysterectomy be the Rule

LOw Grade Serous Ovarian Carcinoma and Uterine Involvement : Should hYSTerectomy be the Rule

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05741554
Acronym
LOGYST
Enrollment
28
Registered
2023-02-23
Start date
2021-09-01
Completion date
2022-10-10
Last updated
2023-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Grade Serous Ovarian Carcinoma, Serous Ovarian Carcinoma

Keywords

Serous ovarian carcinoma, Low grade serous ovarian carcinoma, Fertility sparring surgery, Hysterectomy

Brief summary

Investigators studied a population of 28 low grade serous ovarian carcinoma treated in Hospices civils de Lyon between 2000 and 2022. The primary objective is to determinate the rate of myometrial involvement by the cancer at pathology examination. Then, investigators compared patients with or without myometrial involvement : survival parameters, predictive factors of myometrial involvement (age, CA 125 level, surgery characteristics, pathology characteristics).

Interventions

OTHERRate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.

Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE

Inclusion criteria

* Inclusion Criteria : * 18 years old or more * low grade serous ovarian cancer (MDACC classification) * Grade 1 serous ovarian carcinoma (Silverberg classification) *

Exclusion criteria

: * no sufficient data available * grade 2 and 3 serous ovarian carcinoma

Design outcomes

Primary

MeasureTime frameDescription
Percentage of myometrial involvementAfter pathology examination, average 2 to 3 weeks after cytoreductive surgeryMyometrial involvement after pathology examination

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026