Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients.

Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients. Clinical and Biochemical Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05739838

Enrollment

Registered

2023-02-22

Start date

2021-04-01

Completion date

2023-05-31

Last updated

2023-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Metastatic, Orthodontic Tooth Movement, Periodontal Diseases

Keywords

Rate of orthodontic tooth movement, Osteiocalsine

Brief summary

To investigate the effect of Low Level Laser therapy on orthodontic tooth movement of periodontally compromised patients by evaluating the rate of orthodontic tooth movement and the level of Osteocalcin in the gingival crevicular fluid.

Detailed description

Low-Level laser therapy has been reported as an effective adjunct to non surgical periodontal treatment for inflammation control and tissue reparation in patients with periodontitis. Previous studies have shown that application of low-level laser therapy reduced pocket depth and decreased the inflammatory process through regulatory control of inflammatory cytokines level, therefore this study will investigate the effect of low-level laser on the periodontal tissue .Accelerating orthodontic tooth movement is one of the primary demand in orthodontics to prevent side effects as root resorption, caries and decreased patient compliance . Numerous researchers have also studied the use of LLLT in accelerating orthodontic tooth movement and have considered the laser to be effective while others achieved the opposite . Hence, This study is aiming to investigate the effects of LLLT in accelerating tooth movement.

Interventions

DEVICEBiolase ;Low Level Laser

Low Level laser ,940 nm

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Intervention model description

ten patients with periodontally affected teeth subjected to low level laser therapy

Eligibility

Sex/Gender

ALL

Age

25 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* No systemic disease. * No history medication (antibiotics and/or anti inflammatory) in the previous 4 months. * Self motivated patients with acceptable oral hygien.

Exclusion criteria

* Previous orthodontic treatment * Aggressive periodontitis * Smokers * pregnant patients

Design outcomes

Primary

Measure	Time frame	Description
Rate of orthodontic tooth movement	6 months	Rate of mandibular canine retraction

Secondary

Measure	Time frame	Description
Osteocalcin level in GCF	6 months	Gingival Crevicular Fluid samples will be collected from al target teeth in both groups to detect osteocalcin level after start of orthodontic treatment and at the end of the study

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026