Diabetes, Metabolic Disease
Conditions
Brief summary
This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract on blood sugar management in subhealth people.
Interventions
DIETARY_SUPPLEMENTPumpkin seed extract (Low dose)
Pumpkin seed extract standardized with specific peptides (300 mg/day)
DIETARY_SUPPLEMENTPumpkin seed extract (High dose)
Pumpkin seed extract standardized with specific peptides (600 mg/day)
DIETARY_SUPPLEMENTPlacebo
Placeo (300 mg/day)
Sponsors
Taipei Medical University
Greenyn Biotechnology Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Intervention model description
Parallel Assignment
Eligibility
Sex/Gender
ALL
Age
20 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Fasting blood sugar levels from 100 to 125 mg/dL * Glycated hemoglobin levels from 5.7 to 6.4% * 2-hour OGTT levels from 140 to 199 mg/dL
Exclusion criteria
* Pregnant women or preparing for pregnancy. * Lactating women. * Women gave birth 6 months before the study. * Poor kindy funciton * Severe cardiovascular or other chronic diseases * Patients with type I or II diabetes * Poor compliance * Alcohol abuser * Using anti-diabetic or weight managent supplements * Blood transfusion three months before the study * Pumpkin seed allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Biochemical analysis | Baseline up to 12 weeks | Changes in fasting blodd sugar levels of 60 pariticpants will be analyzed between baseline and week 12. |
| Hormone analysis | Baseline up to 12 weeks | Changes in GLP-1 levels of 60 pariticpants will be analyzed between baseline and week 12. |
Countries
Taiwan
Contacts
Primary ContactMing-Shun Wu, MD
Outcome results
None listed