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Lap-guided vs Us-guided TAP Block in Pediatric Laparoscopy

Laparoscopy-guided Versus Ultrasound-guided Transversus Abdominis Plane (TAP) Block in Pediatric Laparoscopy: a Randomized, Controlled Trial

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05737394
Enrollment
52
Registered
2023-02-21
Start date
2024-06-01
Completion date
2024-12-31
Last updated
2024-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

tap block, laparoscopy, pediatric surgery

Brief summary

Transversus Abdominis Plane (TAP) block is commonly used to control pain in laparoscopic procedures. It is usually administered with ultrasound guide but it can be also administered with laparoscopic assistance under direct visualization. Aim of the present study is determining if the lap-assisted TAP is superior to the us-guided TAP Block in pain control in the immediate postoperative phase as well at 1 and 6 hours post surgery.

Detailed description

Although pain in laparoscopic procedures has been demonstrated to be inferior to that of laparotomic ones, it is still produced because of rapid distension of peritoneum, visceral manipulation, irritation and traction of vessels and phrenic nerves, presence of residual gas and inflammatory mediators. Analgesia can be achieved with multimodal techniques, which include oral or intravenous drugs as well as loco-regional anesthesia techniques. The abdominal wall has three muscle layers: external and internal obliques, and transversus abdominis. They are innervated by mixed somatic nerves that course between the transversus abdominis and the internal oblique muscles. Transversus Abdominis Plane Block is a regional analgesia technique which consists of injecting local anaesthetics between the transversus abdominis and internal oblique muscles, providing analgesia to the parietal peritoneum, skin and muscles of the anterior abdominal wall. It can provide benefit in both open and laparoscopic procedures and it is a safe technique, with a very low reported rate of complications. Three major techniques are used to perform the Transversus Abdominis Plane (TAP) block-a landmark-based, an ultrasound-guided, and a surgical- placed TAP block. Although the landmark technique is easy to perform, it might be complicated by inadvertent intraperitoneal organ damage. Surgically administered Transversus Abdominis Plane (TAP) blocks have been performed by surgeons intraoperatively using the transperitoneal approach, accessing the Transversus Abdominis Plane (TAP) from the inside of the abdominal wall. Direct visualization of the needle and local anaesthetic spread may help to increase the accuracy as well as eliminating the risk of intraabdominal organ injury and is technically less difficult. It is however necessarily placed after incision and pneumoperitoneum establishment. Ultrasound-guided Transversus Abdominis Plane (TAP) block on the other side can be performed prior to incision and pneumoperitoneum, thus avoiding nociception from the very beginning. Aim of the present prospective, randomised, single center controlled study is to compare postoperative analgesic efficacy of laparo-assisted vs ultrasound-guided Transversus Abdominis Plane (TAP) block in pediatric laparoscopic procedures. Primary outcome will be the comparison of pain scores between groups upon arrival to Post-Anesthesia Care Unit (PACU). Secondary outcomes are: * pain scores at 1 and 6 hours after surgery * general anesthesia requirements, as defined by Minimum Alveolar Concentration-hour (MAC\_hour) * intraoperative opiod consumption * complication rates * time to block completion

Interventions

PROCEDURELaparoscopic-guided TAP Block

Laparoscopically-assisted placement of block

Ultrasound-assisted placement of block

Sponsors

Vittore Buzzi Children's Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
0 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Age\<= 18 yrs * Elective or urgent laparoscopic surgical procedures including hernia repair, appendectomy, cholecystectomy, piloromyotomy, Nissen fundoplication, varicocelectomy * ASA Status I and II

Exclusion criteria

* absence of parental consent * ASA Status III-VI * Presence of neurological disability affecting spontaneous mobility * Previous surgical procedures on the abdominal wall (e.g. gastroschisis repair) * Foreseen surgical duration bigger than 4 hours * Conversion to laparotomy * Use of concomitant other regional anesthesia technique (e.g. neuraxial or peripheral)

Design outcomes

Primary

MeasureTime frameDescription
Pain scores in PACUPost-Anesthesia Care Unit - immediately after end of surgeryPain will be measured with FLACC scale (0-10 points; 0 no pain, 10 maximal pain) by operators blinded to the TAP technique

Secondary

MeasureTime frameDescription
Pain scores at 1 and 6 hours post-opfirst 6 hours post - opComparison of pain scores measured with FLACC scale (0-10 points; 0 no pain, 10 maximal pain)by operators blinded to the TAP technique
Intraoperative opioids requirementsIntraoperativeComparison of need for additional boluses of intraoperative opioids if HR raises more than 10% of baseline
General anesthetic requirementsIntraoperativeComparison of MAC-hour in the two groups
Time to Block completionIntraoperativeComparison of time needed to place the block between two groups

Countries

Italy

Contacts

Primary ContactAnna Camporesi, M.D.
anna.camporesi@gmail.com+393355793744

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026