Prostate Cancer
Conditions
Brief summary
Clinical proof of concept of dual-frequency ultrasound imaging for detection and visualization of prostate cancer.
Detailed description
Prospectively recruited patients before prostatectomy and/or definitive radiotherapy will be included in the study. Dual-frequency ultrasound imaging will be compared to standard transrectal ultrasound and MRI. Imaging of primary tumor with dual-frequency ultrasound technology including the use of microbubble contrast-media. A prostate biopsy and blood sample will be taken from each patient, for histopathology and explorative biomarkers.
Interventions
DEVICESURF
Dual-frequency ultrasound
Sponsors
Norwegian University of Science and Technology
University of Oslo
The Research Council of Norway
Oslo University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18 years onwards * Signed written informed consent to perform rectal and transperineal ultrasound
Exclusion criteria
* N/A
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical proof of concept of dual-frequency ultrasound imaging for detection and visualization of prostate cancer. | 1 day | Sensitivity and specificity outcome measures |
Countries
Norway
Outcome results
None listed