Non-small Cell Lung Cancer Stage IIIA
Conditions
Keywords
Machine-learning, Resected early stage Non-small Cell Lung Cancer
Brief summary
Early-stage non small cell lung cancer represents 20-30% of all non small cell lung cancer and is characterized by a high survival probability after surgical resection. However, considering stage IA-IIIA non small cell lung cancer, a relapse rate of about 50% is observed, with a different survival probability on the basis of tumor node metastasis status, although patients within the same tumor node metastasis stage exhibit wide variations in recurrence rate. There are currently no validated prognostic biomarkers able to identify patients with a high risk of relapse.
Detailed description
This study will use data from an already available cohort of patients enrolled in the Resting study (a project funded by TRANSCAN in 2018) as a training set and data from a new concurrent cohort as validation set.
Interventions
OTHERResected non small cell lung cancer
plasma sample, tissue sample and computed tomography scan images
Sponsors
University Hospital, Toulouse
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient with an early stage of non small cell lung cancer * Indication of surgical resection * Patient able to understand and give his consent * Patient affiliated to the health insurance
Exclusion criteria
* Patient with another cancer in the last 5 years * Patient with an allergy to the contrast medium * Patient under legal protection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Algorithm for disease free survival | 18 months | Analysis on a training cohort of resected early-stage non small cell lung cancer |
Countries
France
Contacts
Primary ContactJulien MAZIERES, MD, PhD
Outcome results
None listed