Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects

Clinical and Radiographic Evaluation of Advanced Platelet Rich Fibrin and Open Debridement in Management of Periodontal Suprabony Defects

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05730153

Enrollment

Registered

2023-02-15

Start date

2021-11-21

Completion date

2022-07-26

Last updated

2023-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis, Adult

Brief summary

in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement

Detailed description

two groups of patients with suprabony defects, one will be treated with advanced platelet-rich fibrin in conjunction with open debridement and the other will be treated with open debridement alone. subjects will be evaluated for evidence of bone formation after 6 months of therapy

Interventions

BIOLOGICALadvanced PRF

advanced PRF+ surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* patients with periodontal suprabony defects.

Exclusion criteria

* pregnant females. * smokers. * systemic disease that contraindicate surgery

Design outcomes

Primary

Measure	Time frame	Description
clinical evaluation	6 months	Rate of probing pocket depth reduction

Secondary

Measure	Time frame	Description
radiographic evaluation	6 months	Rate of bone formation by digital radiography

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026