Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05728294

Enrollment

Registered

2023-02-15

Start date

2019-02-01

Completion date

2023-03-31

Last updated

2023-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Brief summary

Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly. Little is known on the type of peripheral nerve block to perform so that optimal postoperative analgesia is provided with minimum impact on the motor function. This randomised controlled double-blinded trial tested the hypothesis that a femoral nerve block provides superior analgesia than a sciatic nerve block after proximal tibial osteotomy.

Interventions

PROCEDUREFemoral nerve block with ropivacaine 0.5%, 20 ml

Femoral nerve block under ultrasound guidance with ropivacaine 0.5%, 20 ml

PROCEDURESciatic nerve block with ropivacaine 0.5%, 20 ml

Sciatic nerve block under ultrasound guidance with ropivacaine 0.5%, 20 ml

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Intervention model description

Two groups: femoral nerve block or sciatic nerve block with ropivacaine

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* proximal tibial osteotomy

Exclusion criteria

* femoral or sciatic nerve deficit, * pre-existing peripheral neuropathy, * chronic pain diagnosis, * pregnancy, * identified contraindications to peripheral nerve block (e.g., local anesthetic allergy, coagulopathy, or infection at the block site).

Design outcomes

Primary

Measure	Time frame	Description
Intravenous morphine consumption	24 hours after surgery	Intravenous morphine consumption (mg)

Secondary

Measure	Time frame	Description
Intravenous morphine consumption	2 hours after surgery	Intravenous morphine consumption (mg)
rest pain score	2 hours after surgery	pain score at rest (visual analogue scale, 0-10)
dynamic pain score	2 hours after surgery	pain score on movement (visual analogue scale, 0-10)
Rate of postoperative nausea and vomiting	2 hours after surgery	number of events/total number of patients

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026