Optimal PEEP in Pediatric Patients Under 17 Years of Age.

Determination of Optimal Positive End-expiratory Pressure in Prone Position During General Anesthesia Using Electrical Impedance Tomography in Pediatric Patient Under 17 Years of Age

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05726877

Enrollment

Registered

2023-02-14

Start date

2022-10-17

Completion date

2024-08-31

Last updated

2023-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilation Therapy; Complications

Brief summary

This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate the hemodynamic stability.

Interventions

OTHERventilation strategy

Titrating positive end-expiratory pressure

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

0 Years to 16 Years

Healthy volunteers

Inclusion criteria

* patients who are scheduled to undergo general anesthesia in the prone position * patients who are in age under 17 years

Exclusion criteria

* had cyanosis or chronic respiratory failure * had respiratory distress syndrome or bronchopulmonary dysplasia * had laryngotracheal diseases * had pulmonary hypertension * receiving oxygen therapy

Design outcomes

Primary

Measure	Time frame	Description
Optimal positive end-expiratory pressure (PEEP)	10 minutes after intubation	result of decremental PEEP trial

Secondary

Measure	Time frame	Description
regional respiratory system compliance	60 minutes after prone positioning	respiratory parameters measured by EIT device
overdistension or atelectasis	10 minutes after intubation	respiratory parameters measured by EIT device
end-expiratory lung volume	10 minutes after intubation	respiratory parameters measured by EIT device
end-expiratory lung impedance	10 minutes after intubation	respiratory parameters measured by EIT device
Impedance tidal variation	10 minutes after intubation	respiratory parameters measured by Electrical Impedance Tomography (EIT) device
center of ventilation	10 minutes after intubation	respiratory parameters measured by EIT device
vital signs	10 minutes after intubation	blood pressure (mmHg)
arterial blood gas analysis, if patients has arterial catheter	10 minutes after intubation & 60 minutes after prone positioning	oxygen and cardon dioxide tension
regional ventilation delay	10 minutes after intubation	respiratory parameters measured by EIT device

Countries

South Korea

Contacts

Primary ContactHee-Soo Kim, M.D., Ph.D.

dami0605@snu.ac.kr02-2072-3664

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026