Predialytic Chronic Kidney Disease
Conditions
Keywords
Chronic kidney disease
Brief summary
CKD is a strong risk factor for cardiovascular disease and mortality , As in adults, cardiovascular disease occurs in some children with CKD before they reach ESRD as well as after
Detailed description
This work aims to study the electrophysiological changes in cardiovascular system in children with predialytic CKD. ECG is important in detection of cardiac rhythm abnormalities, cardiac conduction defects and detection of myocardial ischemia
Interventions
DEVICEHolter
24 hour electrocardiography
Sponsors
Sohag University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
1 Years to 15 Years
Healthy volunteers
No
Inclusion criteria
Age 1 to 15 year children with predialytic chronic kidney disease GFR.\>15 ml\\min per 1.73m2 , stages 1, 2, 3, 4 according to (KDOQI stages).
Exclusion criteria
* Age \>15 year On regular dialysis GFR\<15 ml\\min per 1.73m2, Stage 5 according to (KDOQI stages). Children with known cardiovascular disease or known arrhythmia Patients on the potential medication affecting ECG result as B-blocker, antipsychotics , antidepressant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate variability | One year | Sinus tachycardia or bradycardia |
| changes in QT interval | One year | Prolonged QT interval in ECG |
| QRS duration | One year | Increase or decrease in ECG |
Countries
Egypt
Contacts
Primary ContactWethab K Mohamed, Pediatric resident
Backup ContactShaimaa M Mahmoud, Assistant professor
Outcome results
None listed