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Upper Airways Cephalometric Measures Compared to Skeletal Class and Divergence

A Retrospective Cephalometric Study on Upper Airways Changes Compared to Skeletal Angle Class and Divergence: a Retrospective Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05725980
Enrollment
120
Registered
2023-02-13
Start date
2023-02-12
Completion date
2023-03-26
Last updated
2023-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skeletal Malocclusion

Keywords

Upper airways dimensions, Skeletal Class, Skeletal Divergency

Brief summary

The aim of the present study is to investigate the baseline upper airways dimensions in adult patients belonging to all skeletal classes

Detailed description

Lateral cephalometric radiographs of adult orthodontic patients referring for orthodontic consultation at the Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy, will be collected for the study according to the inclusion criteria. For each lateral cephalometric radiograph, a cephalometric tracing will be performed with DeltaDent software (version 2.2.1, Outside Format, Spino d'Adda, Italy). Riedel's ANB angle \[Riedel 1952\] has been adopted to determine patients' skeletal class. Steiner's SN\^GoGn angle \[Steiner 1953\] will be used to evaluate skeletal divergence. Biprotrusion will be assessed for SNA \> 84° and SNB \> 82°, while biretrusion for SNA \< 80° and SNB \< 78°. Sample size calculation was performed with soft palate length as primary outcome. Considering alpha = 0.05 and power = 95%, an expected mean value of 31.05 with a standard deviation of 4.16 was hypothesized, with an expected mean difference of 3.34 \[Sprenger et al. 2017\], therefore 40 patients per group were required. Statistical analysis will be conducted with R® software (version 3.1.3 R Development Core Team, R Foundation for Statistical Computing, Wein, Austria). For each cephalometric measure belonging to the three skeletal classes, descriptive statistics (mean and standard deviation) will be calculated. Appropriate statistical tests will be used to assess data normality and multiple comparisons. Linear regressions will be performed between upper airways diameters and SNA, SNB, ANB, SN\^GoGn, ANSPNS\^GoGn, PT, PL, sex and age.

Interventions

DIAGNOSTIC_TESTCephalometric analysis

Cephalometric analysis will be performed evaluating upper airways landmarks.

Sponsors

Andrea Scribante
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients with permanent dentition * Caucasian patients * Patients with one lateral cephalometric digital radiograph executed in Natural Head Position (patients were asked to keep the teeth in contact and the lips relaxed).

Exclusion criteria

* maxillo-facial traumas * nasopharyngeal pathologies * craniofacial dysmorphisms * orthognatic surgery * radiographs not performed in Natural Head Position * unsuitable radiographs

Design outcomes

Primary

MeasureTime frameDescription
NL (nasopharynx length)BaselineDistance between Ad1 and PNS
PD (nasopharynx depth)BaselineLine parallel to bispinal plane and connecting PNS and the posterior margin of pharynx
SPAS (Superior Pharyngeal Airway Space)BaselineFrom the half of the posterior wall of soft palate (MMP) perpendicularly to the closest point on the posterior of the posterior wall of the pharynx
MAS (Mean Airway Space)BaselineU1-U2 distance
PAS min (Pharyngeal Airway Space minimum)BaselineT1-T2 distance along Go-B parallel line
IAS (Inferior Airway Space)BaselineFrom the superior margin of the epiglottis (Ph1) to the closest perpendicular point on the posterior wall of the pharynx
LPW (Lateral Pharyngeal Wall)BaselineDistance between epiglottic vallecula (Va1) and the posterior wall of pharynx perpendicular to Va1
PTBaselineSoft palate thickness
PLBaselineSoft palate length
MPH (Mandibular Plane - Hyoid bone)BaselineDistance from the most anterior and superior point of the hyoid bone (H1) perpendicular to mandibular plane

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026