Neurodevelopmental Disorders
Conditions
Brief summary
This study will investigate the effect of physical activity on autism spectrum disorder (ASD) in individuals with ASD of different age groups through measuring the hemodynamic, heart activity and respiratory system parameters.
Detailed description
One hundred participants will be included in this study. One hundred typically developed children or control group and one hundred children with ASD group. The age range of participants will be 4 - 18 years old. The participants in both control and ASD groups will be randomly divided into 4 subgroups according to their age (4-7 years old, 7-10 years old, 10-13 years old and, 14-18 years old). Also, ASD group will be categorized according to the symptoms severity using the childhood autism rating scale (CARS). Participants will be excluded if they have any intellectual disability (IQ ≤ 70), co-morbid medical or psychiatric disorders, pervasive developmental disorders (PDD) or Attention-deficit hyperactivity disorders (ADHD). They will also be excluded if they are taking any medications which to affect cardiovascular system, respiratory system, or arousal and balance or any other contraindications to exercises. Wechsler Intelligence Scale for Children-Fourth Edition24 will be used to assess the Intelligence Quotient (IQ).
Interventions
OTHERPhysical Therapy
The participant will walk for 3-minutes at this speed as a warming up period. After these 3-minutes, the speed will be increased gradually up to 5-6 km/minute under the supervision of parents and therapist. The children will perform 10-minute running at this speed. After this, the cooling down exercise will be performed for 3-minutes. The speed will be decreased for 2 km/ minute and gradually stop.
Sponsors
University of Jazan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Intervention model description
A single- blinded randomized controlled study design will be used, the exercise program will be administrated for four weeks, three times per week, and sixteen minutes per session. Heart rate, ECG, Measurements of respiration, and blood pressure will be measured three times every session: at rest before starting exercises (baseline), directly after finishing exercises, and 15 minutes after finishing exercises.
Eligibility
Sex/Gender
ALL
Age
4 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
1. Children with ASD group with the age range of participants will be 4 - 18 years old 2. Typically developed children with the age range of participants will be 4 - 18 years old
Exclusion criteria
Participants will be excluded if they have the following: * any intellectual disability (IQ ≤ 70) * co-morbid medical or psychiatric disorders. * pervasive developmental disorders (PDD) or Attention-deficit hyperactivity disorders (ADHD). * They will also be excluded if they are taking any medications which to affect cardiovascular system, respiratory system, or arousal and balance or any other contraindications to exercises.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ECG measurements | One minute | A wearable device will be used to collet cardiac ECG data. |
| Measurements of respiration | 5 minutes | Portable Respiratory Monitor will be used to measure the respiratory activity. |
| Blood pressure measurement | 5 minutes | Manual sphygmomanometer will be used to measure the blood pressure. |
Countries
Saudi Arabia
Outcome results
None listed