Renal Stone
Conditions
Brief summary
Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones
Interventions
Extracorporeal shock wave lithotripsy will given to the patients
PROCEDUREExtracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.
Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy will be given to the patients
Sponsors
Services Hospital, Lahore
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* single upper ureteric stone * size ranging from 6-15 mm * stones history less than 6 months
Exclusion criteria
* Patients with urinary tract infection * multiple ureteric stones, * presence of a ureteric stricture distal to the stone, * previous unsuccessful ESWL, * concomitant use of calcium channel blockers or alpha-adrenergic antagonists * patients with abnormal coagulation profile
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| stone clearance | 4 weeks | Number of patients cleared from ureteric stones |
Countries
Pakistan
Outcome results
None listed